Results 101 to 110 of about 28,463 (245)

Combining the α1-Adrenergic Receptor Antagonist, Prazosin, with the β-Adrenergic Receptor Antagonist, Propranolol, Reduces Alcohol Drinking More Effectively Than Either Drug Alone

Alcoholism: Clinical and Experimental Research, 2014
Background Evidence suggests that activation of the noradrenergic system may contribute to alcohol drinking in animals and humans. Our previous studies demonstrated that blocking α1-adrenergic receptors with the antagonist, prazosin, decreased alcohol ...
D. Rasmussen, Lauren E Beckwith, C. Kincaid, J. Froehlich   +3 more
semanticscholar   +1 more source

Prazosin differentially affects NREM sleep in 3.5-month-old TgCRND8 and NTg mice. [PDF]

, 2015
Time spent in NREM sleep during the 2-hour period following administration of the α1-adrenergic antagonist, prazosin, at 1 (A), 2 (B) and 5 (C) mg/kg versus vehicle in 3.5-month-old NTg and TgCRND8 mice.
Jessica Colby-Milley (755301), Antoine Adamantidis (586786), Rémi Quirion (64487), Sonia Jego (292109), Chelsea Cavanagh (755302), John C. S. Breitner (366830)   +5 more
core   +1 more source

Effect of adrenergic blockers, carvedilol, prazosin, metoprolol and combination of prazosin and metoprolol on paracetamol-induced hepatotoxicity in rabbits

Indian Journal of Pharmacology, 2014
Objectives: To evaluate hepatoprotective potential of carvedilol, prazosin, metoprolol and prazosin plus metoprolol in paracetamol-induced hepatotoxicity.
M. Zubairi, J. Ahmed, Sawsan S. Al-Haroon   +2 more
semanticscholar   +1 more source

Preoperative management of pheochromocytoma with prazosin: report of three cases [PDF]

, 1986
We used prazosin (alpha-blocker) for preoperative management of three patients with pheochromocytoma. All patients had episodic hypertension with headache and palpitation. The first dose of prazosin caused blood pressure to drop in one of three patients,
佐々木, 美晴, 小松, 洋輔, 金丸, 洋史, 武縄, 淳   +3 more
core  

Within patient comparison of prazosin and UK-33,274. A new alpha-adrenoceptor-antagonist [PDF]

, 1982
Eleven patients with uncomplicated essential hypertension received increasing single daily doses of UK-33,274, a new alpha-1 adrenoceptor antagonist, and prazosin for 4 days, in a open cross-over study.
de Leeuw, P. W., Ligthart, J. J., Birkenhäger, W. H., Smout, A. J.   +3 more
core   +1 more source

Limitation of infarct size by decrease of afterload with prazosin [PDF]

, 1983
To investigate the possibility of limiting infarct size by decreasing afterload 32 normotensive patients with uncomplicated acute myocardial infarction (AMI) were put on prazosin and compared with 32 control patients.
Alexandris, A. T., Tzannetis, G. C., Karlas, E. N., Kalogeropoulos, C. K., Kolettis, M. T.   +4 more
core  

Alpha-Adrenergic blockade in vasotonic angina: Lack of efficacy of specific alpha1-receptor blockade with prazosin [PDF]

, 1983
To clarify the possible role of the alpha1-adrenergic receptor in angina due to coronary artery spasm, a double-blind, randomized, placebo-controlled trial of the specific alphai-antagonist, prazosin, was performed.
Bernard, Yvonne D., Robertson, Rose Marie, Robertson, David, Carr, R. Keith   +3 more
core   +1 more source

Influence of various ligands on ³H-prazosin and ¹²⁵I-HEAT dissociation. [PDF]

, 2013
Panel A: Dissociation of 3H-prazosin (2 nM) binding to α1A-AR (1 µg) in the presence of prazosin (10 µM, black), prazosin plus ρ-Da1a (2.5 µM, blue), prazosin plus adrenaline (2 mM, red) and prazosin plus EPA (150 µM, green).
Alain Lorphelin (437265), Céline Rouget (74217), Carole Fruchart-Gaillard (158020), Arhamatoulaye Maïga (437260), Elodie Marcon (158051), Charles Marchetti (422794), Roger J. Summers (437267), Bronwyn A. Evans (437268), Maud Larregola (437262), Dana S. Hutchinson (347410), Bernard Gilquin (437263), Laurent Bellanger (437266), Jon Merlin (437261), Nicolas Gilles (158040), Evelyne Lajeunesse (437264), Denis Servent (158060)   +15 more
core   +1 more source

Prazosin Stimulates the Release of Hepatic Triacylglycerole Lipase Caused from Primary-culture Rat Hepatocytes [PDF]

, 2011
Prazosin is an alpha 1 adrenoceptor antagonist, and it is used as an antihypertensive agent. The effects of prazosin on the activity of hepatic triacylglycerole lipase (HTGL) are not fully understood.
46228, 46229, Kerakawati, Rie, Nakamura, Tetsuya, 46230, Morita, Tetsuo   +5 more
core   +1 more source

Effects of prazosin on coronary and left ventricular dynamics in conscious dogs. [PDF]

, 1982
The left ventricular (LV) and coronary vascular effects of prazosin, a drug that reduces peripheral vascular resistance by blocking postsynaptic alpha receptors, were examined in conscious dogs. Prazosin, 0.07 mg/kg/min i.v.
S F Vatner, P Macho
core   +1 more source