Results 81 to 90 of about 28,463 (245)
Alterations to VEGF-A and TSP-1 with elevated CORT and concomitant prazosin treatment. [PDF]
, 2016 RNA or protein was isolated from the TA muscle after 1W or 2W of CORT with or without concurrent prazosin treatment. Taqman qPCR was used to assess the mRNA levels of VEGF-A (A,B) and TSP-1 (D,E), while VEGF-A protein was assessed by ELISA (C) and TSP-1 ...
Ghoncheh Abdifarkosh (3353291) +6 more
core +1 more source
Comparison of alpha-2 agonist versus alpha-1 antagonist for post-traumatic stress disorder–associated nightmares in pediatric patients [PDF]
Mental Health ClinicianIntroduction Posttraumatic stress disorder (PTSD) in children and adolescents has a high prevalence of accompanying sleep disturbances. Currently, pediatric treatment of PTSD-related nightmares is extrapolated from adult studies.
Seher Khalid, PharmD +2 more
doaj +1 more source
Brain sparing in fetal growth restriction: The double‐edged sword of fetal hypoxaemia
The Journal of Physiology, Volume 604, Issue 15, Page 6259-6280, 1 August 2026.Abstract figure legend The double‐edged sword of brain sparing. Fetal hypoxaemia triggers a coordinated adaptive response characterised by redistribution of cardiac output toward essential organs, including the brain, and a reduction in overall metabolic activity to preserve oxygen supply.
Beth J. Allison +3 more
wiley +1 more source
Treatment of nightmares with prazosin: a systematic review [PDF]
, 2012 Nightmares, frequently associated with posttraumatic stress disorder and clinically relevant in today's world of violence, are difficult to treat, with few pharmacologic options.
Espinel, Zelde +3 more
core +1 more source
Alcohol, Clinical and Experimental Research, Volume 50, Issue 7, July 2026.This cohort study examined whether GLP‐1 receptor agonist prescriptions are associated with alcohol use among NIH All of Us participants. Those with current GLP‐1RA prescriptions showed modestly lower AUDIT‐C scores compared to those with future prescriptions. GLP‐1RAs may reduce alcohol consumption by reducing drinking frequency.
Benjamin Tyndall +12 more
wiley +1 more source
Effects of prazosin treatment on ethanol- and sucrose-seeking and intake in P rats [PDF]
, 2011 Background: Previous studies show that prazosin, an α 1-adrenergic receptor antagonist, decreases alcohol drinking in animal models of alcohol use and dependence and in alcohol-dependent men.
Verplaetse, Terril Lee
core +1 more source
The Role of Central Catecholaminergic Systems in Regulation of Food Intake of Chicks
The Journal of Poultry Science, 2001 To clarify catecholaminergic systems on the regulation of food intake in the neonatal chick, we examined the effects of intracerebroventricular (ICV) injection of prazosin (α1-adrenoceptor antagonist), yohimbine (α2-adrenoceptor antagonist ...
Takashi Bungo +4 more
doaj +1 more source
Medical Journal of Australia, Volume 224, Issue 7, July 2026.ABSTRACT NSW Poisons Information Centre data identified 1030 deliberate prazosin self‐poisonings over 11 years, rising from 13 to 170 per year (2014–2024). Young women predominated, likely due to expanded off‐label (but accepted) psychiatric use of prazosin. Better evidence on benefits of off‐label use is needed to justify increasing risks.
Olivia B. E. Lal +2 more
wiley +1 more source
Chronic Treatment with Prazosin Causes a Subtype-specific Increase in the α1-Adrenoceptor Density of the Stressed Rat Cerebral Cortex [PDF]
, 1997 The effects of chronic treatment with prazosin and of immobilization stress on the α1-adrenoceptor subtypes in rat cerebral cortex have been examined.
Jun Zhu +3 more
core +1 more source
Effects of bcrp and p-gp modulators on the penetration of aflatoxin b1 into the mouse brain [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 This study was conducted to determine whether the plasma and brain concentrations of AFB1 are affected by the modulation of P-gp and BCRP using zosuquidar (ZQR) and prazosin (PRZ), respectively. In this study, a total of 40 healthy adult male BALB/c mice
TRAS B +5 more
doaj +1 more source