Results 71 to 80 of about 19,342 (211)

The Role of Central Catecholaminergic Systems in Regulation of Food Intake of Chicks

The Journal of Poultry Science, 2001
To clarify catecholaminergic systems on the regulation of food intake in the neonatal chick, we examined the effects of intracerebroventricular (ICV) injection of prazosin (α1-adrenoceptor antagonist), yohimbine (α2-adrenoceptor antagonist ...
Takashi Bungo, Ryuichi Ando, Sin-Ichi Kawakami, Atsushi Ohgushi, Mitsuhiro Furuse   +4 more
doaj   +1 more source

Effects of MDMA on body temperature in humans [PDF]

, 2014
Hyperthermia is a severe complication associated with the recreational use of 3,4-methylenedioxymethamphetamine(MDMA, Ecstasy). In this review, the clinical laboratory studies that tested the effects of MDMA on body temperature are summarized.
Liechti, Matthias E.
core   +1 more source

Chronic cerebral hypoperfusion exacerbates amyloid and tau pathology by impairing glymphatic transport via AQP4‐ and VEGF‐mediated pathways: insights from a vascular to mixed‐type dementia model

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Chronic cerebral hypoperfusion (CCH) is a major contributor to cognitive impairment; however, its underlying mechanisms remain poorly understood. METHODS We investigated CCH‐induced glymphatic dysfunction and neurodegeneration in amyloid precursor protein (APP)/presenilin 1 (PS1) and wild‐type mice.
Jia‐Hung Chen, Ching‐Wen Chang, You‐Yin Chen, Chih‐Hao Yang, Wen‐Bin Yang, Yi‐Chen Hsieh, Yao‐Wen Liang, Ssu‐Ju Li, Chaur‐Jong Hu   +8 more
wiley   +1 more source

Effects of bcrp and p-gp modulators on the penetration of aflatoxin b1 into the mouse brain [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017
This study was conducted to determine whether the plasma and brain concentrations of AFB1 are affected by the modulation of P-gp and BCRP using zosuquidar (ZQR) and prazosin (PRZ), respectively. In this study, a total of 40 healthy adult male BALB/c mice
TRAS B, CETIN G, UNEY K, DIK B, CORUM O, ATALAY S   +5 more
doaj   +1 more source

Prazosin + Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in P Rats with a Protracted History of Extensive Voluntary Alcohol Drinking, Dependence, and Multiple Withdrawals [PDF]

, 2015
Background Prazosin (PRZ, an α1-adrenergic receptor antagonist) and naltrexone (NTX, a non-specific opioid receptor antagonist) each decrease alcohol drinking when administered to rats selectively-bred for high voluntary alcohol drinking (alcohol ...
Froehlich, Janice C., Kincaid, Carrie L., Rasmussen, Dennis D.   +2 more
core   +1 more source

Managing Antidepressant‐Induced Hyperhidrosis With Vitamin E: An Over‐the‐Counter Supplement–Based Approach

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Excessive sweating is a common side effect of antidepressants, affecting approximately 22% of patients. Antidepressant‐induced excessive sweating (ADIES) can significantly impair quality of life and medication adherence. This case report explores the use of Vitamin E as a novel adjunct treatment for ADIES.
Saad Nazir, Mahnoor Azmat, Neha Prathivadi, Divyaraj Bavishi, Yasin Ibrahim   +4 more
wiley   +1 more source

The α2-adrenergic receptor agonist, clonidine, reduces alcohol drinking in alcohol-preferring (P) rats [PDF]

, 2014
Evidence suggests that noradrenergic signaling may play a role in mediating alcohol-drinking behavior in both rodents and humans. We have investigated this possibility by administering clonidine to alcohol-drinking rats selectively bred for alcohol ...
Alexander, Laura, Federoff, David, Froehlich, Janice C., Malone, Julia, Rasmussen, Dennis D.   +4 more
core   +1 more source

Glymphatic System Dysfunction in Central Nervous System Diseases

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Glymphatic Dysfunction in Neurological Disorders: The glymphatic system is a brain‐wide clearance system that removes neurotoxic waste via AQP4‐mediated CSF‐ISF exchange. Dysfunction through AQP4 mislocalization, BBB injury, and inflammation annihilates clearance and causes acute (stroke, TBI) and chronic disease.
Anwar Zahran, Omar Abu‐Khazneh, Mohammad Bdair, Orabi Hajjeh, Mohammed AbuBaha, Waseem Shehadeh, Ameer Awashra, Ibrahim Alazizi, Raya Fuqha, Sakeena Saife, Hasan Fuqha, Fathi Milhem, Husam Hamshary, Dana Abuzahra, Umar Shuaib   +14 more
wiley   +1 more source

Comparison of 7 α1-adrenoceptor Antagonists in Patients with Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia:A Short-term Crossover Study [PDF]

, 2013
A crossover study was conducted to identify the best α1-adrenoceptor (α1AR) antagonist for individual patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). One hundred thirteen patients (mean age 70.8 years)
Araki, Motoo, Araki, Tohru, Monden, Koichi   +2 more
core   +1 more source

The Use of Non‐Selective Beta‐Blockers in Cirrhotic Portal Hypertension

Portal Hypertension &Cirrhosis, Volume 5, Issue 1, Page 96-105, March 2026.
Non‐selective beta‐blockers (NSBBs) reduce portal pressure and play a key role in preventing variceal bleeding, managing ascites, and preventing hepatocellular carcinoma (HCC) in cirrhotic patients. Their clinical application requires individualized strategies and further optimization of indications. ABSTRACT Liver cirrhosis is the end stage of various
Tong Bu, Tianyuan Yang, Qi Wang
wiley   +1 more source