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Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia have reduced life expectancy, with increased risks of stroke, cardiovascular disease and diabetes, while babies from a pre-eclamptic pregnancy have increased risks of preterm ...
Evdokia Dimitriadis+10 more
openaire +5 more sources
By far the commonest cause of hypertension in pregnancy is pre-eclampsia, but other causes must not be forgotten.
Sandra Dean+2 more
openaire +3 more sources
Acute maternal infection and risk of pre-eclampsia: a population-based case-control study. [PDF]
BACKGROUND: Infection in pregnancy may be involved in the aetiology of pre-eclampsia. However, a clear association between acute maternal infection and pre-eclampsia has not been established. We assessed whether acute urinary tract infection, respiratory
A Conde-Agudelo+31 more
core +8 more sources
AbstractPre-eclampsia is a multifactorial and multisystemic disease specific to gestation. It is classically diagnosed by the presence of hypertension associated with proteinuria manifested in a previously normotensive pregnant woman after the 20th week of gestation.
José Carlos Peraçoli+14 more
openaire +9 more sources
Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancy [PDF]
Obesity increases preeclampsia risk. Adipose tissue inflammation may contribute to the clinical syndrome of pre-eclampsia. We compared adipose tissue macrophage infiltration and release of pro-inflammatory adipokines in pre-eclampsia and healthy ...
Bray, Jack+6 more
core +1 more source
Differential expression of microRNA-206 and its target genes in pre-eclampsia [PDF]
Objectives: Pre-eclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify novel circulating miRNAs in maternal plasma that may be ...
Akehurst, Christine+12 more
core +1 more source
Patient journey during and after a pre-eclampsia-complicated pregnancy:a cross-sectional patient registry study [PDF]
OBJECTIVES: To gain insight into the patient journey through a pre-eclampsia-complicated pregnancy. DESIGN: Cross-sectional patient registry study. SETTING: Online patient registry initiated by the Preeclampsia Foundation.
Abrenica-Keffer, Norlisa+7 more
core +1 more source
Inter-pregnancy interval and risk of recurrent pre-eclampsia: systematic review and meta-analysis [PDF]
Background: Women with a history of pre-eclampsia have a higher risk of developing pre-eclampsia in subsequentpregnancies. However, the role of the inter-pregnancy interval on this association is unclear.Objective: To explore the effect of inter ...
Agustín Ciapponi+5 more
core +3 more sources
Tests for predicting complications of pre-eclampsia: A protocol for systematic reviews [PDF]
Background Pre-eclampsia is associated with several complications. Early prediction of complications and timely management is needed for clinical care of these patients to avert fetal and maternal mortality and morbidity.
Coomarasamy, Arri+6 more
core +4 more sources