Results 91 to 100 of about 81,119 (304)

Polarised press reporting about HIV prevention: Social representations of pre-exposure prophylaxis in the UK press [PDF]

, 2016
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Pre-exposure prophylaxis is a novel biomedical HIV prevention option for individuals at high risk of HIV ...
Jaspal, R, Nerlich, Brigitte, Nerlich, B, Jaspal, Rusi; id_orcid, Jaspal, Rusi   +4 more
core   +1 more source

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

Animal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat, Chatsuree Suksamai, Dhammika Leshan Wannigama, Kent Doi, Wiwat Chancharoenthana, Asada Leelahavanichkul   +5 more
wiley   +1 more source

Prescribing of Medication to Prevent Glucocorticoid Harms in Patients With Polymyalgia Rheumatica: A Cross‐Sectional Study and Two Emulated Target Trials in the Clinical Practice Research Datalink Aurum

Arthritis &Rheumatology, EarlyView.
Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig, David Jenkinson, James Bailey, Samantha Hider, Ian C. Scott, Sara Muller   +5 more
wiley   +1 more source

ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Combined Anterior Cruciate Ligament Reconstruction With Bone‐Patellar Tendon‐Bone Autograft and Anatomical Lateral Collateral Ligament and Proximal Tibiofibular Joint Reconstruction Using Semitendinosus Allograft

Arthroscopy Techniques, EarlyView.
Abstract Multiligamentous knee injuries involving anterior cruciate ligament rupture and lateral‐sided instability, including proximal tibiofibular joint instability and lateral collateral ligament deficiency, present unique challenges in restoring knee stability.
Ryan J. Froom, Alexi J. Panos, Nate J. Dickinson, Molly E. Kessenich, Matthew T. Provencher   +4 more
wiley   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Risk factors for delayed post-exposure prophylaxis among Japanese travelers with animal bite exposure: A multicenter retrospective study

Travel Medicine and Infectious Disease
Introduction: Rabies is a fatal zoonotic disease; however, no comprehensive studies have been conducted on rabies prevention among Japanese travelers with animal exposure providing detailed information on pre-travel consultation, pre-exposure prophylaxis
Takehiro Hashimoto, Kei Yamamoto, Taku Ogawa, Issaku Nakatani, Nobuyuki Mishima, Shinji Fukushima, Akira Nishizono   +6 more
doaj   +1 more source

Health Students' Knowledge of Pre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP): A Scoping Review

Pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) are important tools for the prevention and reduction of human immunodeficiency virus (HIV) infections.
Laura Candeias dos Santos
core   +1 more source

PrEP counseling center

, 2023
This is a brochure for the PrEP Counseling Center. The PrEP Counseling Center is a virtual environment where clients who are prescribed PrEP (pre-exposure prophylaxis) in the Health Department Clinics can receive comprehensive PrEP ...
South Carolina Department of Health and Environmental Control
core  

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source