Results 51 to 60 of about 141,118 (333)

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Awareness of, willingness to use, and experiences with Pre-exposure prophylaxis among youth in Nigeria

BMC Health Services Research
Background Youth (ages 14–24) in Nigeria have disproportionately high rates of new HIV infection. Pre-exposure prophylaxis could substantially reduce new infections among youth but has not been scaled up.
Titilola Gbaja-Biamila, Chisom Obiezu-Umeh, Ucheoma Nwaozuru, Nora E. Rosenberg, Mesoma Igbokwe, David Oladele, Adesola Z. Musa, Ifeoma Idigbe, Donaldson Conserve, Suzanne Day, Kadija Tahlil, Jason Ong, Kathryn Muessig, Susan Nkengasong, Hong Xian, Joseph D. Tucker, Oliver Ezechi, Juliet Iwelunmor   +17 more
doaj   +1 more source

A systematic review of adherence to oral pre-exposure prophylaxis for HIV – how can we improve uptake and adherence?

BMC Infectious Diseases, 2018
Introduction Oral pre-exposure prophylaxis (PrEP) is an effective strategy to reduce the risk of HIV transmission in high risk individuals. However, the effectiveness of oral pre-exposure prophylaxis is highly dependent on user adherence, which some ...
David Sidebottom, Anna Mia Ekström, Susanne Strömdahl   +2 more
doaj   +1 more source

Perceptions about HIV pre-exposure prophylaxis among healthcare professionals in Spain (PERPPRES Study) [PDF]

Farmacia Hospitalaria, 2016
Objective: To determine the level of support, knowledge and perceptions of pre-exposure prophylaxis (PrEP) by Infectious Disease Specialists and Hospital Pharmacists in Spain.
Javier Sánchez-Rubio Ferrández, José Manuel Martínez Sesmero, Herminia Navarro Aznárez, Sergio Fernández Espínola, Ismael Escobar Rodríguez, José Manuel Ventura Cerdá   +5 more
doaj   +1 more source

Nanoparticle Encapsulation for Antiretroviral Pre-Exposure Prophylaxis [PDF]

Journal of Nanotechnology and Materials Science, 2017
HIV continues to be one of the greatest challenges facing the global health community. More than 36 million people currently live with HIV and, in 2015 2.1 million new infections were reported globally. Pre-Exposure Prophylaxis (PrEP) prevents HIV infection by inhibiting viral entry, replication, or integration at the primary site of pathogenic ...
Khandalavala, Karl, Mandal, Subhra, Pham, Rachel, Destache, Christopher J., Shibata, Annemarie   +4 more
openaire   +2 more sources

Syndemics and the PrEP Cascade: Results from a Sample of Young Latino Men Who Have Sex with Men. [PDF]

, 2019
Young Latino men who have sex with men (MSM) are a highly vulnerable population for HIV infection. Pre-exposure prophylaxis (PrEP) is a novel biomedical HIV prevention tool that may aid in reducing the disparity in HIV incidence among Latino MSM. However,
Blashill, Aaron J, Blumenthal, Jill, Brady, John P, Horvath, Keith J, Moore, David J, Morris, Sheldon, Rodriguez-Diaz, Carlos E, Rooney, Benjamin M, Safren, Steven A   +8 more
core   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

A community perspective on pre‐exposure prophylaxis [PDF]

Journal of the International AIDS Society, 2014
The history of pre‐exposure prophylaxis (PrEP) is notable for being a community rather than industry‐driven development. This talk will review this history, covering factors that include community demand, study results, regulatory challenges, commercial interests and practical issues of public health. It will also look at some of the controversies that
openaire   +2 more sources

Depression and Oral FTC/TDF Pre-exposure Prophylaxis (PrEP) Among Men and Transgender Women Who Have Sex With Men (MSM/TGW). [PDF]

, 2016
We conducted a longitudinal and cross-sectional analysis of depressive symptomology in iPrEx, a randomized, placebo-controlled trial of daily, oral FTC/TDF HIV pre-exposure prophylaxis (PrEP) in men and transgender women who have sex with men. Depression-
Amico, K Rivet, Avelino-Silva, Vivian I, Burns, David, Chodacki, Piotr, Defechereux, Patricia A, Fernandez, Telmo, Glidden, David V, Grant, Robert M, iPrEx Study Team, Liu, Albert Y, Mayer, Kenneth H, McMahan, Vanessa M, Mehrotra, Megha, Vargas, Lorena   +13 more
core   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source