Results 111 to 120 of about 241,576 (378)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
X-Rays in the Orion Nebula Cluster: Constraints on the Origins of Magnetic Activity in Pre-Main-Sequence Stars [PDF]
, 2002 A recent observation of the Orion Nebula Cluster with the ACIS instrument on board the Chandra X-Ray Observatory detected 1075 sources, 525 of which are pre-main-sequence (PMS) stars with measured bulk properties such as bolometric luminosities, masses ...
E. Feigelson +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Active Young Stars in the LAMOST–Kepler Survey
The Astrophysical Journal Supplement SeriesIn the early stages of their lives, young stars harbor diverse processes exhibiting strong signatures, making them ideal targets for investigating stellar accretion, dynamo actions, and exoplanet formation.
FuKun Xu, Shenghong Gu, Yue Xiang
doaj +1 more source
X-ray emission from pre-main sequence stars with multipolar magnetic fields [PDF]
, 2023 Kieran A Stuart, S. G. Gregory
openalex +1 more source
A kinematic study of the Taurus-Auriga T association [PDF]
, 2006 Aims: This is the first paper in a series dedicated to investigating the kinematic properties of nearby associations of young stellar objects. Here we study the Taurus-Auriga association, with the primary objective of deriving kinematic parallaxes for ...
Bertout, Claude, Genova, Francoise
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Polarization: A Method to Reveal the True Nature of the Dusty S-Cluster Object (DSO/G2)
Galaxies, 2018 There have been different scenarios describing the nature of a dusty source, noted as Dusty S-cluster Object (DSO) or G2, orbiting around the Galactic centre super-massive black hole.
Banafsheh Shahzamanian +4 more
doaj +1 more source
Lithium Depletion in Fully Convective Pre-Main-Sequence Stars [PDF]
, 1996 We present an analytic calculation of the thermonuclear depletion of lithium in contracting, fully convective, pre-main-sequence stars of mass M ≲ 0.5 M☉. Previous numerical work relies on still uncertain physics (atmospheric opacities and convection, in
L. Bildsten +3 more
semanticscholar +1 more source
Pre-Main Sequence Stars Seen by ISO [PDF]
Space Science Reviews, 2005 Observations of pre-main sequence objects (T Tauri, Herbig Ae/Be and FU Orionis stars) obtained with the instrumentation on board the Infrared Space Observatory (ISO) are reviewed. All the observations have been mainly carried out by using the two spectrographs SWS and LWS, adopting their low resolution modes and such data have been used both for lines
openaire +1 more source