Results 111 to 120 of about 226,792 (352)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Two Young Eclipsing Binaries in Orion with Temperatures and Radii Affected by Spots and Third Bodies

open access: yesThe Astronomical Journal
In this work we present a model of two young eclipsing binaries in the Orion complex. Both heavily spotted, they present radii and temperatures that are in disagreement with the predictions of standard stellar models.
Marina Kounkel, Keivan G. Stassun
doaj   +1 more source

X-Ray Spectral Characterization of the Young Cygnus OB2 Population

open access: yesThe Astrophysical Journal Supplement Series, 2023
We analyze the X-ray spectra of the ∼8000 sources detected in the Cygnus OB2 Chandra Legacy Survey (this focus issue), with the goals of characterizing the coronal plasma of the young low-mass stars in the region and estimating their intrinsic X-ray ...
E. Flaccomio   +9 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

MASS LOSS IN PRE-MAIN-SEQUENCE STARS VIA CORONAL MASS EJECTIONS AND IMPLICATIONS FOR ANGULAR MOMENTUM LOSS [PDF]

open access: yes, 2012
We develop an empirical model to estimate mass-loss rates via coronal mass ejections (CMEs) for solar-type pre-main-sequence (PMS) stars. Our method estimates the CME mass-loss rate from the observed energies of PMS X-ray flares, using our empirically ...
A. Aarnio, S. Matt, K. Stassun
semanticscholar   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

The Nature of X-Rays from Young Stellar Objects in the Orion Nebula Cluster—A Chandra HETGS Legacy Project

open access: yesThe Astrophysical Journal
The Orion Nebula Cluster (ONC) is the closest site of very young (∼1 Myr) massive star formation The ONC hosts more than 1600 young and X-ray bright stars with masses ranging from ∼0.1–35 M _⊙ .
Norbert S. Schulz   +12 more
doaj   +1 more source

The Effects of Stellar Wind, Rotation Velocity, and Overshoot Parameters on The Evolution of Massive Stars using MESA: Case Study of MPG 324, MPG 355, MPG 682

open access: yesSpektra: Jurnal Fisika dan Aplikasinya
Massive stars (over 8 solar masses) undergo intricate cosmic journeys. Their evolution, shaped by parameters like stellar wind, rotation velocity, and overshoot, generally includes the pre-main sequence, main sequence, and post-main sequence phases.
Alin Hafizhah Adira, Aprilia
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

A Census of B[e] Supergiants

open access: yesGalaxies, 2019
Stellar evolution theory is most uncertain for massive stars. For reliable predictions of the evolution of massive stars and their final fate, solid constraints on the physical parameters, and their changes along the evolution and in different ...
Michaela Kraus
doaj   +1 more source

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