Results 91 to 100 of about 12,001 (263)

Inactive Longitude and Superflare in the Active Single-lined Pre-main-sequence Binary V2279 Cyg

open access: yesThe Astrophysical Journal
Young, solar-like stars in the pre-main-sequence (PMS) stage exhibit vigorous magnetic activity that significantly influences their circumstellar environments and the processes of planetary formation and evolution.
Xueying Hu   +9 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Magnetic Activity of Pre-main Sequence Stars [PDF]

open access: yesSymposium - International Astronomical Union, 2004
I review here recent advances in our understanding of magnetic activity in pre-main sequence (PMS) protostars and T Tauri stars. Results are based on recent imaging, spectroscopic and temporal studies of nearby star forming regions from the Chandra X — ray Observatory and XMM — Newton, including a first look at an ultradeep Chandra exposure of the ...
openaire   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Disk-locking Regulates Stellar Rotation in Young Clusters: Insights from NGC 2264

open access: yesThe Astrophysical Journal
Many young clusters possess extended main sequences, a phenomenon commonly ascribed to stellar rotation. However, the mechanism behind their very wide stellar rotation distributions remains unclear.
Yutian Bu   +3 more
doaj   +1 more source

Modeling the origin of the rotation of massive stars

open access: yesAstronomy & Astrophysics
Context. We explore the origins behind the rotation rates of massive stars, accounting for the fact that in contrast to their low-mass siblings, most massive stars do not have detectable magnetic fields.
Oliva André   +5 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Gaia23bab: A New EXor

open access: yesThe Astrophysical Journal
On 2023 March 6, the Gaia telescope alerted a 2 mag burst from Gaia23bab, a young stellar object in the Galactic plane. We observed Gaia23bab with the Large Binocular Telescope obtaining optical and near-infrared spectra close in time to the peak of the ...
T. Giannini   +13 more
doaj   +1 more source

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