Results 91 to 100 of about 22,441 (303)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

X-Ray Evolution of Young Stars: Early Dimming and Coronal Softening in Solar-mass Stars with Implications for Planetary Atmospheres

The Astrophysical Journal
X-ray and ultraviolet (XUV) emission from young stars plays a critical role in shaping the evolution of planetary atmospheres and the conditions for habitability.
Konstantin V. Getman, Eric D. Feigelson, Vladimir S. Airapetian, Gordon P. Garmire   +3 more
doaj   +1 more source

Chemically peculiar stars on the pre-main sequence

Context. The chemically peculiar (CP) stars of the upper main sequence are defined by spectral peculiarities that indicate unusual elemental abundance patterns in the presence of diffusion in the calm, stellar atmospheres.
Faltová, N., Jadlovský, D., Svačinková, K., M. Vítková, Xia, C., Hümmerich, S., Vítková, M., S. Hümmerich, L. Kueß, M. Mesarč, Kueß, L., N. Faltová, M. Labaj, Ramezani, T., K. Svačinková, K. Bernhard, P. Mondal, Mesarč, M., Mondal, P., Prišegen, M., D. Jadlovský, C. Xia, E. Paunzen, J. Supíková, Supíková, J., Bernhard, K., M. Prišegen, Paunzen, E., Labaj, M., T. Ramezani   +29 more
core   +1 more source

Age-related observations of low mass pre-main and young main sequence stars [PDF]

, 2009
This overview summarizes the age dating methods available for young sub-solar mass stars. Pre-main sequence age diagnostics include the Hertzsprung-Russell (HR) diagram, spectroscopic surface gravity indicators, and lithium depletion; asteroseismology is
Hillenbrand, Lynne A.
core  

Pre-Main-Sequence evolution of rotating low-mass stars

, 1989
The evolutionary behaviour of rotating low-mass stars in the mass range 0.2 and 0.9M ⊙ has been investigated during the pre-Main-Sequence phase. The angular momentum is conserved locally in radiative regions and totally in convective regions, according ...
KIZILOGLU, N, Kızıloğlu, Nilgün
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Spectral Variability of Herbig Ae Star V1295, Aquila

Galaxies
This article presents the results of long-term spectral studies of the unusual Herbig Ae star V1295 Aql. The variability in the spectrophotometric parameters of the emission and absorption components of the hydrogen lines Hα, Hβ, and D Na I—and of ...
Hemayil Adigozalzade, Silva Jarvinen, Swetlana Hubrig, Ulviyya Bashirova, Nariman Ismailov   +4 more
doaj   +1 more source

Polarization: A Method to Reveal the True Nature of the Dusty S-Cluster Object (DSO/G2)

Galaxies, 2018
There have been different scenarios describing the nature of a dusty source, noted as Dusty S-cluster Object (DSO) or G2, orbiting around the Galactic centre super-massive black hole.
Banafsheh Shahzamanian, Andreas Eckart, Michal Zajacek, Monica Valencia-S., Nadeen B. Sabha   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Pre-Main Sequence Stars Seen by ISO [PDF]

Space Science Reviews, 2005
Observations of pre-main sequence objects (T Tauri, Herbig Ae/Be and FU Orionis stars) obtained with the instrumentation on board the Infrared Space Observatory (ISO) are reviewed. All the observations have been mainly carried out by using the two spectrographs SWS and LWS, adopting their low resolution modes and such data have been used both for lines
openaire   +1 more source