Results 51 to 60 of about 22,441 (303)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
An HST Study of the Substellar Population of NGC 2024
The Astrophysical Journal, 2023 We performed an HST/WFC3-IR imaging survey of the young stellar cluster NGC 2024 in three filters probing the 1.4 μ m H _2 O absorption feature, characteristic of the population of low-mass and substellar-mass objects down to a few Jupiter masses.
Massimo Robberto +8 more
doaj +1 more source
The pre-main-sequence star IP Persei [PDF]
Astronomy & Astrophysics, 2001 We present the results of high- and low-resolution spectroscopic and broadband multicolour photometric observations of the emission-line A-type star IP Per. Significant variations of the Balmer line profiles and near-IR brightness are detected.
A. S. Miroshnichenko +6 more
openaire +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Pulsation in pre-main sequence stars [PDF]
Proceedings of the International Astronomical Union, 2015 AbstractAsteroseismology has been proven to be a successful tool to unravel details of the internal structure for different types of stars in various stages of evolution well after birth. We can now show that it has similar power for pre-main sequence (pre-MS) objects.
openaire +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Asteroseismology of pre-main sequence stars [PDF]
Communications in Asteroseismology, 2009 Intermediate-mass pre-main sequence (PMS) stars cross the instability region on their way to the main sequence and can become pulsationally unstable. The δ Scuti-like PMS pulsators populate the same area in the Hertzsprung-Russell (HR) diagram as the classical δ Scuti stars.
openaire +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The Astrophysical JournalWe present results from simultaneous far-ultraviolet (FUV) and near-ultraviolet (NUV) observations of T Tauri stars (TTSs) in the Taurus molecular cloud with UVIT/AstroSat. This is the very first UVIT study of TTSs.
Prasanta K. Nayak +6 more
doaj +1 more source