Results 91 to 100 of about 211,616 (238)

Pre-mRNA Splicing [PDF]

Molecular Cell, 2003
Jurica, Melissa S., Moore, Melissa J.
openaire   +1 more source

Three exonic variants in the PHEX gene cause aberrant splicing in a minigene assay

Frontiers in Genetics
Background: X-linked hypophosphatemia (XLH, OMIM 307800) is a rare phosphorus metabolism disorder caused by PHEX gene variants. Many variants simply classified as missense or nonsense variants were only analyzed at the DNA level.
Fengjiao Pan, Ruixiao Zhang, Xuyan Liu, Xiaomeng Shi, Qing Xin, Qing Xin, Dan Qiao, Changying Li, Yan Zhang, Mengke Chen, Wencong Guo, Wencong Guo, Shufang Luan, Leping Shao, Leping Shao   +14 more
doaj   +1 more source

Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing [PDF]

, 2012
Adenosine-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the transcriptome in metazoa. In addition to wide-spread editing in non-coding regions protein recoding by RNA editing allows for fine tuning of protein ...
Ales Balik, Altschul, Andrew C. Penn, Arzumanov, Arzumanov, Balik, Bass, Birney, Brusa, Carver, Daniel, Darty, Dominski, Egebjerg, Eisen, Enstero, Feldmeyer, Gallo, Ge, Greger, Hamada, Heasman, Higuchi, Higuchi, Hogg, Ingo H. Greger, Jepson, Jubin, Katoh, Kent, Kwak, Laurencikiene, Maas, Moulton, Peng, Reenan, Rice, Rosenthal, Rueter, Ryman, Schoft, Sommer, Stephens, Summerton, Summerton, Summerton, Tariq, Traynelis, Valente, Venkatesh, Yamashita, Yang   +51 more
core   +1 more source

Selective Histocompatibility Leukocyte Antigen (Hla)-A2 Loss Caused by Aberrant Pre-mRNA Splicing in 624mel28 Melanoma Cells [PDF]

, 1999
Zhigang Wang, Francesco M. Marincola, Licia Rivoltini, Giorgio Parmiani, Soldano Ferrone   +4 more
openalex   +1 more source

Mechanism for cryptic splice site activation during pre-mRNA splicing. [PDF]

, 1990
Kristin K. Nelson, M R Green
openalex   +1 more source

DEAD-box protein Ddx46 is required for the development of the digestive organs and brain in zebrafish.

PLoS ONE, 2012
Spatially and temporally controlled gene expression, including transcription, several mRNA processing steps, and the export of mature mRNA to the cytoplasm, is essential for developmental processes.
Shunya Hozumi, Ryo Hirabayashi, Akio Yoshizawa, Mitsuko Ogata, Tohru Ishitani, Makiko Tsutsumi, Atsushi Kuroiwa, Motoyuki Itoh, Yutaka Kikuchi   +8 more
doaj   +1 more source

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors [PDF]

, 1998
The SR proteins are essential metazoan pre-mRNA splicing factors that can also influence the selection of alternative 5' splice sites in a concentration-dependent manner.
Caceres, J. F., Franza, B. R., Hanamura, A., Krainer, A. R., Mayeda, A.   +4 more
core   +1 more source

In vitrosplicing of fibronectin pre-mRNAs [PDF]

, 1990
Pamela A. Norton, Richard O. Hynes
openalex   +1 more source

Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process.

PLoS ONE, 2019
Alternative splicing diversifies mRNA transcripts in human cells. While the spliceosome pairs exons with a high degree of accuracy, the rates of rare aberrant and non-canonical pre-mRNA splicing have not been evaluated at the nucleotide level to ...
Derrick J Reynolds, Klemens J Hertel
doaj   +1 more source

To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in Plants

Frontiers in Plant Science, 2019
Gene expression in eukaryotes is controlled at multiple levels, including transcriptional and post-transcriptional levels. The transcriptional regulation of gene expression is complex and includes the regulation of the initiation and elongation phases of
Ying Cao, Ligeng Ma
doaj   +1 more source