Results 221 to 230 of about 270,676 (398)

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

Advanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng, Jianan Xu, Linglong Qin, Xingbo Wang, Chenhe Lu, Yanming Huang, Da Liu, Yan Yan, Weiren Dong, Pinglong Xu, Jiyong Zhou   +10 more
wiley   +1 more source

Pre-mRNA Splicing Functions in Plant Sexual Reproduction Development. [PDF]

Plants (Basel)
Shao D, Gao X, Wei Y.
europepmc   +1 more source

The implications of alternative pre-mRNA splicing in cell signal transduction. [PDF]

Exp Mol Med, 2023
Choi S, Cho N, Kim KK.
europepmc   +1 more source

A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction. [PDF]

, 1994
Or Gozani, James G. Patton, Robin Reed
openalex   +1 more source

Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing

Proceedings of the National Academy of Sciences of the United States of America, 2016
M. Falaleeva, Amadís Pagès, Zaneta Matuszek, Sana' Hidmi, Lily Agranat-Tamir, K. Korotkov, Y. Nevo, E. Eyras, R. Sperling, S. Stamm   +9 more
semanticscholar   +1 more source

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

Advanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang, Fang Li, Jiao Liu, Shu‐Ang Li, Dan‐Hua Liu, Zhuanbin Wu, Pei‐Pei Liu, Wenju Liu, Bin Zhou, Cizhong Jiang, Haibing Zhang, Ying Yu, Jian‐Sheng Kang   +12 more
wiley   +1 more source

SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing. [PDF]

Elife
Govindan A, Conrad NK.
europepmc   +1 more source

Stages in the second reaction of pre-mRNA splicing: the final step is ATP independent. [PDF]

, 1993
David S. Horowitz, John Abelson
openalex   +1 more source

Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo.

Cancer Cell, 2015
C. Shirai, J. Ley, B. S. White, Sanghyun P. Kim, J. Tibbitts, J. Shao, M. Ndonwi, Brian A. Wadugu, E. Duncavage, Theresa Okeyo-Owuor, Tuoen Liu, M. Griffith, S. McGrath, V. Magrini, R. Fulton, C. Fronick, M. O'Laughlin, T. Graubert, M. Walter   +18 more
semanticscholar   +1 more source

ALKBH5‐Mediated M6A Demethylation of G3BP1 Attenuates Ferroptosis Via Cytoplasmic Retention of YBX1/p53 in Diabetic Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
ALKBH5 promoted G3BP1 expression via m⁶A methylation at sites 142/173. G3BP1 interacts with YBX1 and p53, reducing their nuclear translocation and decreasing p53‐mediated SLC7A11 repression. This inhibites cardiomyocyte ferroptosis and mitigates myocardial damage during diabetic ischemia‐reperfusion injury.
Wenyuan Li, Wei Li, Yan Leng, Heng Xu, Zhongyuan Xia, Yao Wang   +5 more
wiley   +1 more source