Results 91 to 100 of about 1,073,946 (296)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Effects of 8 Weeks with Embodied Learning on 5-6-Year-Old Danish Children's Pre-reading Skills and Word Reading Skills: the PLAYMORE Project, DK. [PDF]

Educ Psychol Rev, 2022
Damsgaard L, Nielsen AV, Gejl AK, Malling ASB, Jensen SK, Wienecke J.   +5 more
europepmc   +1 more source

EMBEDDING CRITICAL THINKING THROUGH CRITICAL READING : TEACHING NARRATIVE TEXT IN JUNIOR HIGH SCHOOL [PDF]

, 2017
Penelitian ini bertujuan untuk mengetahui apakah strategi critical reading dapat meningkatkan kemampuan berpikir kritis dan bagaimana strategi critical reading membantu siswa untuk berpikir kritis dalam membaca naratif teks.
Fadhillah, Ajeng Meidina
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Mechanical dissection in an introductory engineering design module [PDF]

, 2010
The introductory design module for first year students in the Department of Mechanical Engineering at the University of Strathclyde uses mechanical dissection as a focus for learning activities that seek to integrate engineering science with the prior ...
Jenkins, Peter, McLaren, A.J.
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Using Content Reading Assignments in a Psychology Course to Teach Critical Reading Skills

Journal of the Scholarship of Teaching and Learning, 2012
Liberal arts students are expected to graduate college with fully developed critical reading and writing skills. However, for a variety of reasons these skills are not always as well developed as they might be - both during and upon completion of college.
Debbie Van Camp, Wesley Van Camp
doaj  

Preparing special educators to teach second language to students with learning disabilities in the United Arab Emirates: an experimental study

Cogent Education
Consistently, it has been reported that children with disabilities struggle to acquire literacy skills. Although there is evidence that students with learning disability are not given requisite support in classrooms, there is limited research on training
Maxwell Peprah Opoku, Maria Efstratopoulou, Fatima Alkatheeri, Haseena Shah, Lydia Haitham Kasem, Amina Khurshid, Eleana Charalambous, Ashraf Moustafa   +7 more
doaj   +1 more source

PENGGUNAAN MEDIA KARTU KATA BERGAMBAR UNTUK MENINGKATKAN KETERAMPILAN MEMBACA PERMULAAN PADA SISWA TUNARUNGU KELAS 2 DI SLBN B GARUT [PDF]

, 2017
Membaca permulaan merupakan dasar untuk memahami simbol-simbol tulisan yang dibutuhkan oleh individu untuk melanjutkan proses keterampilan membaca selanjutnya.
Putriana, Risnawati
core  

Evaluating new approaches to teaching of sight-reading skills to advanced pianists [PDF]

, 2013
This paper evaluates three teaching approaches to improving sight-reading skills against a control in a large-scale study of advanced pianists. One hundred pianists in four equal groups participated in newly developed training programmes (accompanying ...
Zhukov, Katie
core   +1 more source