Results 101 to 110 of about 1,073,946 (296)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Progressing in Tandem: A Sure Start Initiative for Enhancing the Role of Parents in Children's Early Education [PDF]

open access: yes, 2003
The Tandem Project is an educational programme, targeting preschoolers, sponsored by the DfEE Sure Start initiative. It aims to encourage parents from low SES bacgrounds to take a greater role in preparing their children for school. Parents are given a
Evans, D., Ford, R., McDougall, S.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

What Determines Adult Cognitive Skills? Impacts of Pre-Schooling, Schooling and Post-Schooling Experiences in Guatemala [PDF]

open access: yes
Most investigations of the importance of and the determinants of adult cognitive skills assume that (a) they are produced primarily by schooling and (b) schooling is statistically predetermined.
Aryeh D. Stein, Emory University   +7 more
core  

Incidence of Executive Functions on Reading Comprehension Performance in Adolescents [PDF]

open access: yes, 2014
Introducción.La comprensión lectora es una habilidad cognitiva compleja que se ha asocia-do a procesos ejecutivoscomola memoria de trabajo (MT) y la inhibición.
Canet Juric, Lorena   +2 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Family and Consumer Sciences Teacher Educator\u27s Perception of Integration of Reading Skill Instruction [PDF]

open access: yes, 2014
Purpose: The purpose of this study was to determine family and consumer sciences (FACS) teacher educators’ perceptions on the integration of reading skill instruction in secondary FACS courses.
Arnett-Hartwick, Sally E.   +1 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Pengaruh Penerapan Strategi Belajar Preview, Question, Read, Reflect, Ricete, Riview terhadap Keterampilan Membaca Siswa SD [PDF]

open access: yes, 2017
The purpose of the research is to analyse the effect of the USAge of learning strategies preview, question, read, reflect, ricete, review on fifth grade child story reading students' skills in 15th state elementary school in south Pontianak.
Ramadan, A. R. (Arriyanti)
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

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