Results 141 to 150 of about 510,232 (259)
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee +12 more
wiley +1 more source
Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly
W. A. Braden, A. Mcclendon, E. Knudsen
semanticscholar +1 more source
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar +6 more
wiley +1 more source
Beyond the Beam: Exploring Charged Particle Nanoprinting
Charged particle nanoprinting using electrons and ions is highly advanced, offering great potential for research and industry. However, challenges in precursor design and process optimization persist, but also offer great opportunities to drive nanofabrication innovations.
Nicolas Paul Jochmann +2 more
wiley +1 more source
This study highlights the importance of accounting for stoichiometric hydrogen produced when utilizing Si photocatalysts. The stoichiometric contribution is sacrificial reagent dependent and decreases with increasing sterics around the catalyst surface.
Sarrah H. Putwa +4 more
wiley +1 more source
Dynamics of pre-replication complex proteins during the cell division cycle.
S. Prasanth +3 more
semanticscholar +1 more source
Metal Nanoclusters for Cancer Imaging and Treatment
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source
DNA replication origins, ORC/DNA interaction, and assembly of pre-replication complex in eukaryotes.
J. Sun, D. Kong
semanticscholar +1 more source
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila +7 more
wiley +1 more source
This work develops an ultrarobust, flexible, and solvent‐free eutectic gel featuring stretch‐induced orientation. Overcoming hydrogel limitations, the gel achieves record toughness (133.86 MJ m−3) while integrating strain/temperature/capacitive sensing.
Tingzhong Li +5 more
wiley +1 more source

