Results 41 to 50 of about 3,217,762 (308)

Early years : subject profile (SPICe briefing; 11/51) [PDF]

open access: yes, 2011
"This subject profile provides an introduction to services for pre-school children. It updates and expands SB 06/83 published in October 2006. Early Years refers to pre-school education, child health, children‟s social work and childcare.
Kidner, Camilla
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Prospective Pre-School Teachers’ Distance Education Perspectives

open access: yesJournal of Learning and Teaching in Digital Age, 2022
Background: Distance education is a science-based system that supports learner independence through technology. Purpose: The aim of this study is to evaluate the distance education system according to the experiences of prospective teachers studying the preschool education curriculum.
openaire   +3 more sources

Final Report from the Primary phase: pre-school, school and family influences on children’s development during Key Stage 2 (7-11) [PDF]

open access: yes, 2008
The Effective Pre-school and Primary Education project (EPPE 3-11) is Europe’s largest longitudinal study, which uses multi-level modelling to investigate the effects of pre-school and primary education on pupils’ developmental outcomes.
Melhuish, Edward C.   +4 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Pre-school Education Teacher's Opinion about the Implementation of 2013 Pre-school Education Program

open access: yesProcedia - Social and Behavioral Sciences, 2015
AbstractThis research is made to determine pre-school teacher's opinion about the implementation of 2013 pre-school education program. This research is a descriptive study in screening model. The study group consists of 72 pre-school teachers. Datas are collected by using Personal Information Form and the Evaluation Survey of 2013 Pre-school Education ...
Çivik, Sevinç Pişgin   +2 more
openaire   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Importance of pre-school science education

open access: yesSHS Web of Conferences, 2017
Considering this aspect of the study, the objective of the study is determining the importance of science education in pre-school period. In this research, two open-ended questions were asked to the prospective teachers. In these questions, the focus was
Kaçan Sibel Demir, Çelikler Dilek
doaj   +1 more source

The Innovative Early Childhood Education Teacher – A Summary of Own Research

open access: yesMultidisciplinary Journal of School Education, 2017
Content of article by Anna Szkolak The Innovative Early Childhood Education Teacher – A Summary of Own Research is related with the debate on the Polish teacher condition in the situation of the system transformation, changes in the Polish school.
Anna Szkolak
doaj   +1 more source

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