Results 111 to 120 of about 2,341,004 (362)

Effects of Whole-Body Electromyostimulation on Physical Fitness in Postmenopausal Women: A Randomized Controlled Trial [PDF]

, 2020
Whole-body electromyostiulation (WB-EMS) has experienced a boom in recent years, even though its effectiveness is controversial. A sedentary lifestyle is deeply rooted in the European population, mainly in the elderly. This experimental study analyzed the
Beltrán Garrido, José Vicente, Hernández González, Vicenç, Pano-Rodriguez, Alvaro, Reverter Masià, Joaquín   +3 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The legal regime of the martial state in Ukraine and its impact on the conduct of pre-trial investigation: new challenges and their overcoming

Via Inveniendi Et Iudicandi
This article examines the legal regime of the martial state in Ukraine and its impact on the conduct of pre-trial investigations. The article begins with an overview of the current political and legal situation in Ukraine and highlights the importance ...
Valerii Sokurenko, Kateryna Levchenko, Serhii Ablamskyi, Oswaldo Pereira de Lima Jr, Goran Šimić, Vitalii Romaniuk   +5 more
doaj   +1 more source

Механізм діяльності правоохоронних судових органів у досудовому розслідуванні кримінальних корупційних правопорушень [PDF]

, 2018
Бобошко О. М. Механізм діяльності правоохоронних судових органів у досудовому розслідуванні кримінальних корупційних правопорушень / О. М. Бобошко // Lex Portus : юрид. наук. журн. / редкол. : С. В. Ківалов (голов. ред. ради), Б. А. Кормич (голов. ред.),
Boboshko, O., Бобошко, Е. Н., Бобошко, О. М.   +2 more
core  

Early Settlement in European Merger Control [PDF]

, 2016
We analyse the determinants of early settlement between merging parties and the European Commission over remedies that remove concerns of anticompetitive effects.
Aktas, Ashenfelter, Ausubel, Baker, Bebchuk, Bergman, Bougette, Bourjade, Coate, Coate, Coate, Coate, Cooter, Cramton, Davies, Davies, Davies, Dougherty, Duso, Fenn, Fenn, Fenn, Fernández, Fournier, Fournier, Friedman, Fudenberg, Grossman, Ivaldi, Kennan, Kessler, Kessler, Kouliavtsev, Kühn, Lindsay, Lyons, Ormosi, Perloff, Priest, Reinganum, Sobel, Spier, Spier, Ven, Waldfogel   +44 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Detention as a violation of the fundamental right to protection

Науково-інформаційний вісник Івано-Франківського університету права імені Короля Данила Галицького
Purpose. The purpose of the work is to study the current legislation that violates a person’s fundamental right to protection when the preventive measure of detention is chosen for him. Method.
Lototskyi M., Dzundza L.
doaj   +1 more source

Economic issues in a trial of the controlled provision of heroin [PDF]

, 1994
Executive Summary: This paper discusses some economic issues that may be investigated as part of a proposed trial of the controlled provision of heroin in the Australian Capital Territory.
Butler, J.R.G, Neil, Amanda L
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source