Results 161 to 170 of about 2,341,004 (362)

THE PROBLEMS OF REGULATING THE POWERS OF THE PROSECUTOR TO SUPERVISE THE PROCEDURAL ACTIVITIES OF THE BODIES OF INQUIRY AND PRELIMINARY INVESTIGATION

open access: yesХабаршы. Заң сериясы
The article examines the current state of law enforcement practice; theoretical, legal and organizational foundations of the prosecutor's supervision of the criminal procedural activities of the bodies conducting pre-trial investigation; issues of the ...
Г.Н. Мухамадиева   +4 more
doaj  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Application of the principle of retroactivity in ukrainian legislation for commitment of applicable offenses against property

open access: yesНауково-інформаційний вісник Івано-Франківського університету права імені Короля Данила Галицького
Purpose. The purpose of the work is to study the extension of the principle of retroactivity to law-making and law-enforcement practice to the legal system in Ukrainian legislation. Methodology.
Lototskyi M., Dzundza L.
doaj   +1 more source

Проблеми застосування інституту зупинення досудового провадження у діяльності слідчих органів внутрішніх справ [PDF]

open access: yes, 2012
Татаров О. Ю. Проблеми застосування інституту зупинення досудового провадження у діяльності слідчих органів внутрішніх справ / О. Ю. Татаров // Актуальні проблеми політики : зб. наук. пр. / редкол. : С. В. Ківалов (голов. ред..), Л. І.
Tatarov, О.   +2 more
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Legal liability for theft under martial law: substantive and procedural aspects

open access: yesНауково-інформаційний вісник Івано-Франківського університету права імені Короля Данила Галицького
Purpose. The purpose of the work is to analyze changes to criminal legislation and legislation on administrative liability for the secret theft of someone else’s property, further judicial practice on this issue.
Ostrohliad O.
doaj   +1 more source

Home-based tuberculosis contact investigation in Uganda: a household randomised trial. [PDF]

open access: yes, 2019
IntroductionThe World Health Organization (WHO) recommends household tuberculosis (TB) contact investigation in low-income countries, but most contacts do not complete a full clinical and laboratory evaluation.MethodsWe performed a randomised trial of ...
Armstrong-Hough, Mari   +16 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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