Results 71 to 80 of about 2,248 (168)

Reassessing Transketolase Assays: Methodological Considerations for Detecting Functional Thiamine Deficiency

Annals of the New York Academy of Sciences, Volume 1557, Issue 1, March 2026.
Transketolase (TKT) activity provides a functional measure of thiamine status by integrating cofactor availability, enzyme abundance, and catalytic capacity. TKT catalyzes thiamine diphosphate (TDP)‐dependent reactions in the nonoxidative pentose‐phosphate pathway and requires magnesium for optimal activity.
Katie A. Edwards
wiley   +1 more source

Determining the rate and reasons for specimen rejection among specimens referred for HIV viral load determination through referral linkage to Debre Tabor Comprehensive Specialized Hospital, north-central, Ethiopia,2023: Retrospective study

Heliyon
Background: The preanalytical phase encompasses the time between the clinician's test order to the sample being ready for analysis. Of all errors during the laboratory diagnostic process,70 % appeared in the pre-analytical phase. In clinical laboratories,
Ayenew Berhan, Andargachew Almaw, Shewaneh Damtie, Yenealem Solomon, Biruk Legese, Birhanu Getie, Mulat Erkihun   +6 more
doaj   +1 more source

Blood Microsampling for Complete Blood Count: Take Heed of Preanalytical Errors [PDF]

International Journal of Child Health and Nutrition, 2017
Background: The credibility of the result of a complete blood count is closely connected with the preanalytical phase. Objectives: This study evaluated accordance of filling of microtubes with manufacturer’s recommendation and assessed the effect of storage of overfilled and underfilled samples on the results of complete blood count. Design and Methods:
Barbara Koscielniak, Andrzej Zajac, Przemysaaw Tomasik   +2 more
openaire   +2 more sources

Medical errors: Pre-analytical issue in patient safety [PDF]

Journal of Medical Biochemistry, 2010
The last few decades have seen a significant decrease in the rates of analytical errors in clinical laboratories, while a growing body of evidence demonstrates that the pre and post-analytical steps of the total testing process (TTP) are more error-prone
Plebani Mario, Piva Elisa
doaj  

Routine use of a spike‐in DNA in‐process control for foetal RHD genotyping: Testing the real‐world effectiveness of this ‘canary’

Vox Sanguinis, Volume 121, Issue 3, Page 361-369, March 2026.
Abstract Background and Objectives Non‐invasive foetal RHD (fRHD) genotyping is widely implemented to prevent unnecessary administration of antenatal anti‐D prophylaxis. Reliable assay performance is critical. In line with expert recommendations, we validated and implemented an artificial spike‐in extraction control in our previously published assay ...
Renske M. van ’t Oever, Heleen Woortmeijer, Ahmad Javadi, Aicha Ait Soussan, Barbera Veldhuisen, Claudia C. Folman, C. Ellen van der Schoot, Erik H. van Beers, Masja de Haas   +8 more
wiley   +1 more source

What Is Your Diagnosis? Abnormal WDF Scattergram From the Sysmex XN‐1000V in a Cat

Veterinary Clinical Pathology, EarlyView.
Javier Martínez‐Caro, Laura Chaves‐Falcón, Marta Lemos, Xavier Roura, Luis Bosch, Josep Pastor   +5 more
wiley   +1 more source

The Alzheimer's Disease Diagnosis and Plasma Phospho‐Tau217 (ADAPT) study stage 1: Validating clinical cut‐points against CSF and amyloid PET

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION We validated plasma phosphorylated tau (p‐tau)217 cut‐points for Alzheimer's disease (AD) diagnosis using two commercial assays in two biomarker‐defined cohorts and examined influences of pre‐analytical factors and chronic kidney disease (CKD) on p‐tau217 concentrations. METHODS Lumipulse (Fujirebio) and ALZpath (Quanterix) assays
Ashvini Keshavan, Katharine Wiltshire, Ryan Wee, Irene Gorostiaga Belio, Katie Tucker, Melanie Hart, Michael P. Lunn, Michael C. B. David, Laura Rizzo, Omid Sadeghi‐Alavijeh, Patricia Wilson, Daniel P. Gale, Amanda J. Heslegrave, Henrik Zetterberg, Nick C. Fox, Paresh Malhotra, Jonathan M. Schott   +16 more
wiley   +1 more source

Evaluation of Pre-Analytical Errors in Clinical Biochemistry Laboratory of a Tertiary Care Center in India

Journal of Clinical and Basic Research, 2021
Background and objectives: Laboratory medicine is equally challenged by economic and new technological pressures. Clinical laboratories have undergone major change due to advancement of technology, which has improved the decision making of clinicians but
KAPILA GAIKWAD, SOHAN SELKAR
doaj  

Sources of preanalytical errors and the role of training in error prevention

Dicle Medical Journal / Dicle Tip Dergisi, 2012
Amaç: Bu çalışmada, biyokimya ve mikrobiyoloji laboratuarlarına gönderilen örneklerde preanalitik hataların analizi ve eğitimin hata önlemedeki rolü incelenmiştir. Gereç ve yöntem: Sekiz aylık dönem boyunca merkez laboratuarına kabul edilen tüm örnekler retrospektif olarak incelendi. Reddedilen örneklerin dağılımı, preanalitik hata kategorileri (yanlış
ÖZCAN, Oğuzhan, GÜRESER, Ayşe Semra
openaire   +2 more sources

Preanalytical errors in pediatric blood sampling: a systematic review of common challenges and risks

Türk Biyokimya Dergisi
This systematic review aims to identify common preanalytical errors in pediatric blood sampling.
Şenol Şule
doaj   +1 more source