Results 71 to 80 of about 3,707 (182)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, Volume 20, Issue 3, Page 588-610, March 2026.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

AMH standardization and preanalytical phase as two sides of the same coin. [PDF]

JBRA Assist Reprod, 2023
Demirci G, Saçıntı KG, Sönmezer M, Öztürk HS.   +3 more
europepmc   +1 more source

Choice of fixative affects programmed death‐ligand 1 expression in cell blocks from pleural effusions with metastatic pulmonary adenocarcinoma

Cancer Cytopathology, Volume 134, Issue 3, March 2026.
Abstract Background Programmed death‐ligand 1 (PD‐L1) immunocytochemical (ICC) analysis of cell blocks (CBs) has recently emerged in clinical practice. Unlike standardized immunohistochemistry on formalin‐fixed, paraffin‐embedded tissues, cytology involves various preparation methods and fixatives.
Mohammed S. I. Mansour, Louise Pettersson, Rita Pedersen, Ulrich Mager, Kim Hejny, Frida Kronqvist, Anna Aronsson, Tomas Seidal, Levent M. Akyürek, Ivana Kholová   +9 more
wiley   +1 more source

The Influence of Aerobic and Strength Training on Oxidative Stress and Antioxidant Status in Hemodialysis Patients: A Randomized Controlled Trial

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims To investigate the effects of a 6‐month supervised, personalized combined aerobic and resistance training program on oxidative stress, antioxidant capacity, infection‐related biomarkers, and body composition in maintenance hemodialysis (MHD) patients.
Yuwei Chen, Lu Yin, Xinzhou Zhang, Xue Zheng, Lijuan Lan, Liping Sun   +5 more
wiley   +1 more source

Preanalytical errors in emergency department samples: Investigating error sources [PDF]

Journal of Medical Biochemistry, 2020
Background: The presence of preanalytical errors is a recurring fact in all areas of healthcare that send samples to laboratories. Increasing the knowledge of possible sources of error in the preanalytical phase has been the objective of this group ...
Romero Adolfo, Gómez-Salgado Juan, Romero-Arana Adolfo, Gómez-Fernández José Antonio, Cobos Andrés, Ramos María Carmen, Iglesias María Rosa   +6 more
doaj  

The Grey Zone Project: Risk‐Based Classification of ABCD1 Variants in X‐Linked Adrenoleukodystrophy

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Newborn screening (NBS) for X‐linked adrenoleukodystrophy (ALD) enables early identification of boys at risk for adrenal insufficiency (AI) and cerebral ALD (CALD). However, NBS frequently identifies ABCD1 variants of uncertain significance (VUS), which are associated with only borderline‐elevated C26:0‐lysophosphatidylcholine (LPC(26:0 ...
Troy C. Lund, Kelly Miettunen, Yorrick R. J. Jaspers, Caroline Bergner, Joshua L. Bonkowsky, Fabio Bruschi, Julie S. Cohen, Inge M. E. Dijkstra, Florian S. Eichler, Eric J. Mallack, Gajja S. Salomons, Robert Thompson, Davide Tonduti, Keith P. van Haren, Mirjam M. C. Wamelink, Ayelet Zerem, Marc Engelen, Stephan Kemp   +17 more
wiley   +1 more source

Impact and frequency of IV fluid contamination on basic metabolic panel results using quality metrics

Journal of Laboratory Medicine
Clinical laboratories invest substantial time and resources to mitigate measurement error but potential errors during the preanalytical phase of testing are not subjected to the same level of scrutiny. Herein, we assess the proportions of intravenous (IV)
Spies Nicholas C., Farnsworth Christopher W.   +1 more
doaj   +1 more source

Impact of Pneumatic Transport System on Preanalytical Phase Affecting Clinical Biochemistry Results. [PDF]

J Lab Physicians, 2023
Kumari S, Kumar S, Bharti N, Shekhar R.
europepmc   +1 more source

Clinical Application of Peripheral Blood Biomarkers for Solid Tumors

MedComm, Volume 7, Issue 3, March 2026.
Peripheral blood biomarkers provide a minimally invasive, dynamic, and potentially more accurate means to obtain a comprehensive tumor profile. Technologies for detecting them are advancing, and with the help of artificial intelligence, they are being used more and more often for cancer diagnosis, prognostic assessment, and therapeutic monitoring ...
Xinru Tu, Mengyan Tu, Junfen Xu
wiley   +1 more source

Review of Existing Approaches and Potential Role of Pharmacometrics in the Interpretation of Prognostic Circulating Serum Biomarkers in Advanced NSCLC

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Circulating serum biomarkers have prognostic value in patients with advanced NSCLC, yet their potential still remains underappreciated at present. This review discusses classical approaches of biomarker data analysis, highlighting gaps, and summarizing current methodologies to evaluate the relationship between serum biomarkers and clinical ...
Francis Williams Ojara, Yomna M. Nassar, Kimberly Geiger, Madele van Dyk, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft   +6 more
wiley   +1 more source