Results 41 to 50 of about 1,520 (185)

Assessing the performance of large language models when used to determine ASA status of cats and dogs and generate anaesthetic protocols

open access: yesVeterinary Record, EarlyView.
Abstract Background Large language models (LLMs) are emerging as decision‐support tools in human medicine; however, their evaluation in veterinary anaesthesiology remains limited. Methods We retrospectively analysed 225 anonymised feline and canine cases (American Society of Anaesthesiologists [ASA] classifications 1‒5) from Atatürk University ...
Sıtkıcan Okur   +7 more
wiley   +1 more source

Butorphanol Pharmacokinetics Across Species: Meta‐Analysis Integrating Allometric Scaling and Minimal Physiologically Based Pharmacokinetic Modeling

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
mPBPK Allometric Meta‐Analysis (MAMA) of Butorphanol Across 13 Species. ABSTRACT Butorphanol, an opioid agonist–antagonist used in human and veterinary medicine, lacks systematic interspecies comparisons. Butorphanol pharmacokinetics (PK) was assessed across species using a minimal physiologically based PK (mPBPK) model and allometric scaling, termed ...
Ahmed M. Saeed, William J. Jusko
wiley   +1 more source

Dexmedetomidine vs midazolam as preanesthetic medication in children: a meta-analysis of randomized controlled trials

open access: yes, 2015
INTRODUCTION:The preoperative period is a stressing occurrence for most people undergoing surgery, in particular children. Approximately 50-75% of children undergoing surgery develop anxiety which is associated with distress on emergence from anesthesia ...
Frati E   +6 more
core   +1 more source

Clinical Features and Surgical Outcomes of Cats With Presumed Primary Lens Instability: A Retrospective Study of 34 Cases (2018–2022)

open access: yesVeterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective Describe the clinical features, disease progression, and outcomes of presumed primary lens instability (PLI) in cats, and to assess its association with glaucoma. Animals Studied Thirty‐four cats (68 eyes). Procedures Medical records were reviewed for signalment, clinical history, ophthalmic findings, and treatment.
Havi Sarfaty   +5 more
wiley   +1 more source

Pleiotropic effects and pharmacological properties of penehyclidine hydrochloride

open access: yesDrug Design, Development and Therapy, 2018
Yaguang Wang, Yafen Gao, Jun Ma Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People’s Republic of China Background: Penehyclidine ...
Wang Y, Gao Y, Ma J
doaj  

Sedative effect of dexmedetomidine nasal spray combined with midazolam oral solution in children before surgery [PDF]

open access: yes精准医学杂志
Objective To investigate the sedative effect of dexmedetomidine nasal spray combined with midazolam oral solution in children before surgery. Methods A total of 60 children who underwent elective surgery in the Department of Oral and Maxillofacial ...
FANG Yi, ZHOU Wenjuan, HUANG Wensheng, SHEN Dai
doaj   +1 more source

EEG Dynamics in Children Before, During and After General Anesthesia

open access: yesPediatric Anesthesia, Volume 36, Issue 6, Page 641-649, June 2026.
ABSTRACT Background Age‐specific EEG signatures during anesthesia are described in pediatrics, and perioperative monitoring is increasingly advocated; yet most indices and algorithms derive from adult data and may not generalize to early development. Aims The purpose of this study was to characterize perioperative frontal EEGs in young children younger
Maximilian Markus   +3 more
wiley   +1 more source

Analysis of serum biomarkers associated with pain in Spanish greyhounds undergoing ovariohysterectomy

open access: yesVeterinary Record, Volume 198, Issue 9, Page e404-e411, 2/9 May 2026.
Background This study measured serum biomarkers at baseline and during an ovariohysterectomy in healthy female Spanish greyhounds, aiming to enhance the objectivity of current methods for assessing acute postoperative pain in dogs. Methods Blood samples from 20 Spanish greyhounds were collected before drug administration (T0‐baseline).
Rocio Navarrete‐Calvo   +8 more
wiley   +1 more source

Dexmedetomidine vs midazolam as preanesthetic medication in children: a meta-analysis of randomized controlled trials

open access: yes, 2020
What's known • Premedication reduces perioperative anxiety in children. What this article adds • Dexmedetomidine is more effective than midazolam in decreasing preoperative anxiety, postoperative agitation, and in providing more effective ...
Valentina Testa   +8 more
core  

Pregabalin contributes to increased recovery time from isoflurane anaesthesia for magnetic resonance imaging in horses

open access: yesEquine Veterinary Journal, Volume 58, Issue 3, Page 736-746, May 2026.
Abstract Background Pregabalin reduces excitatory neurotransmitter release and is used for anxiolysis in humans, cats, and horses. The effects of pregabalin on equine recovery following isoflurane anaesthesia are unknown. Objectives To determine if pre‐anaesthetic oral pregabalin influences recovery time and/or quality from isoflurane anaesthesia in ...
Abigail Blanton   +8 more
wiley   +1 more source

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