Results 51 to 60 of about 2,624 (248)

Transnasal Ventral Brainstem Epidural Electrical Stimulation Enhances Consciousness in Anesthetized Sheep: A Feasibility Study

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
This study provides the first experimental evidence of a novel transnasal ventral brainstem epidural electrical stimulation approach in anesthetized sheep and demonstrates that this procedure can induce behavioral arousal and cortical electrophysiological changes toward a wake‐like state, holding promise for the treatment of chronic disorders of ...
Bin Liu   +14 more
wiley   +1 more source

Utilidad de la consulta preanestésica para disminuir el grado de ansiedad en pacientes programados para intervención quirúrgica [PDF]

open access: yes, 2017
Treball Final de Grau en Grau en Medicina. Codi: MD1158. Curs: 2016/2017La ansiedad es una reacción compleja que advierte frente a situaciones y estímulos potencialmente peligrosos o percibidos como tales y que permite al individuo adoptar medidas para ...
Olcina Domínguez, Pablo
core  

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz   +10 more
wiley   +1 more source

Pleiotropic effects and pharmacological properties of penehyclidine hydrochloride

open access: yesDrug Design, Development and Therapy, 2018
Yaguang Wang, Yafen Gao, Jun Ma Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University-Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People’s Republic of China Background: Penehyclidine ...
Wang Y, Gao Y, Ma J
doaj  

Expressions of Kisspeptin System and Ki‐67 in the Reproductive Tissues of Cyclic Bitches

open access: yesReproduction in Domestic Animals, Volume 61, Issue 4, April 2026.
ABSTRACT Kisspeptin is a peptide that plays a pivotal role in the central regulation of gonadotropins. It is regarded as a key regulator of reproductive processes, including follicular and luteal development and endometrial remodelling. The objective of this study was to investigate the expression of KISS1, its receptor KISS1R and the proliferation ...
Özgecan Korkmaz Ağaoğlu   +4 more
wiley   +1 more source

Sedative effect of dexmedetomidine nasal spray combined with midazolam oral solution in children before surgery [PDF]

open access: yes精准医学杂志
Objective To investigate the sedative effect of dexmedetomidine nasal spray combined with midazolam oral solution in children before surgery. Methods A total of 60 children who underwent elective surgery in the Department of Oral and Maxillofacial ...
FANG Yi, ZHOU Wenjuan, HUANG Wensheng, SHEN Dai
doaj   +1 more source

Application to Add Midazolam to the Model List of Essential Medicines [PDF]

open access: yes, 2011
Summary statement of the proposal for inclusion The benzodiazepine midazolam has proven sedative, anxiolytic and amnesic properties. It is extensively used for premedication and procedural sedation in both adults and children.
Vet, N.J. (Nienke)   +2 more
core  

How could multimedia information about dental implant surgery effects patients? anxiety level? [PDF]

open access: yes, 2016
To evaluate the effects of different patient education techniques on patients? anxiety levels before and after dental implant surgery. Sixty patients were randomized into three groups; each contained 20 patients; [group 1, basic information given ...
Acar, Ahmet Hüseyin   +2 more
core   +1 more source

Comparison Between Bipolar Diathermy and Coblation Assisted Tonsillectomy in Pediatric Population: A Randomized Experimental Study

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aim Tonsillectomy is one of the most commonly performed surgical procedures on children. Indications for tonsillectomy include recurrent tonsillitis, obstructive sleep apnea, and peritonsillar abscess, among others. Bipolar diathermy and coblation surgeries are the most common used surgeries.
Rabia Azam   +10 more
wiley   +1 more source

Comparison of intranasal versus intravenous midazolam for management of status epilepticus in dogs : a multi‐center randomized parallel group clinical study [PDF]

open access: yes, 2019
Background: The intranasal (IN) route for rapid drug administration in patients with brain disorders, including status epilepticus, has been investigated. Status epilepticus is an emergency, and the IN route offers a valuable alternative to other routes,
Bhatti, Sofie   +22 more
core   +1 more source

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