Results 41 to 50 of about 5,089 (171)
In this population‐based study of 883 women, AMH declined less with age in women with PCOS than in healthy women. Higher AMH may protect older healthy women from T2DM but indicates elevated metabolic risk in younger women with PCOS, supporting its role as a life‐course biomarker for metabolic risk stratification.
Fahimeh Ramezani Tehrani +5 more
wiley +1 more source
Background: BMD-15 is a member of the superfamily of transforming growth factor-beta (TGF-β), which has a determinant role in fertility. This protein is essential for the development of ovarian follicles and acts mainly by binding to its receptor on the
Amene Shekarian +4 more
doaj +1 more source
ABSTRACT The aim of this study was to evaluate the effect of anethole addition to the ovine oocyte in vitro maturation (IVM) medium on viability and chromatin configuration, intracellular production of reactive oxygen species (ROS), enzymatic activity of superoxide dismutase (SOD) and catalase (CAT), as well as the levels of reduced thiols in IVM ...
Anderson Nascimento de Andrade +10 more
wiley +1 more source
The Regulation of Apoptosis in Preantral Ovarian Follicles
Less than 1% of ovarian follicles ever mature to ovulation. The remainder undergo atretic degeneration via apoptosis during development. Though the regulation of antral and preovulatory survival has been studied for many years, very little is known about the regulation of survival and development of preantral follicles.
openaire +2 more sources
Purpose To investigate abnormalities of early folliculogenesis and Anti-Müllerian hormone (AMH) concentrations in polycystic ovary syndrome (PCOS) patients, and to analyze the association between AMH and early-stage follicle densities (FD).
Juan Du +6 more
doaj +1 more source
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi +13 more
wiley +1 more source
Cytohistological Changes of the Apoptosis Ovarian Follicles in the Puberty Mouse Ovary
Apoptosis, as a normal physiological process is active in the ovary of all species of mammals, representing the essential factor in maintaining the homeostasis of this organ.
Liliana Petculescu-Ciochina +2 more
doaj
This study aimed to derive mature oocytes from murine preantral follicles cultured in a biomimetic ovary with a porcine scaffold using decellularization technology.
Eun young Park +4 more
doaj +1 more source
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
Luteinizing hormone receptor knockout mouse: What has it taught us?
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source

