Results 61 to 70 of about 5,344 (205)

Control of the growth and development of murine preantral follicles in a biomimetic ovary using a decellularized porcine scaffold

Materials Today Bio, 2023
This study aimed to derive mature oocytes from murine preantral follicles cultured in a biomimetic ovary with a porcine scaffold using decellularization technology.
Eun young Park, Jin hee Park, Nhu Thi Quynh Mai, Byoung-San Moon, Jung Kyu Choi   +4 more
doaj   +1 more source

Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome

Advanced Science, Volume 13, Issue 23, 23 April 2026.
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu, Yihan Wang, Haiyun Chen, Xinye Yu, Tingyu Wang, Yajing Weng, Meihong Guo, Ying Huang, Gaojian Tao, Wangsen Cao, Yong Wang, Daojuan Wang   +11 more
wiley   +1 more source

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source

A novel method for toxicology: In vitro culture system of a rat preantral follicle

, 2011
Preantral follicle in vitro culture systems have been successfully or nearly successfully established for sheep, pig and mouse, and applied on follicle development and regulation research on reproductive biology and physiology.
null Wang Fei, null Liu Zhen, null Zhu Yuping, null Wan Xuying, null Zhu Jiangbo, null Zhang Tianbao, MA Xili, null Xu Guifeng   +7 more
core   +1 more source

Salidroside Ameliorates Polycystic Ovary Syndrome in Mice by Regulating the AKT/NF‐κB/NLRP3‐HAS2 Axis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Salidroside ameliorates PCOS via inhibiting the ROS‐AKT/NF‐κB axis and suppressing NLRP3 inflammasome activation. It disrupts the NLRP3–LAP‐TGFβ1 interaction to block TGF‐β‐SMAD2/3 signaling and consequent ovarian fibrosis. Together with hyaluronan synthase 2 (HAS2) downregulation, these effects alleviate inflammation and hyaluronan overaccumulation ...
Jing‐hang Li, Shu‐Ming Shi, Li‐Ying Liu, Yu‐Yan He, Guan‐Lin Jia, Lin‐Yi Qu, Zhi‐Chao Chi, Jia‐hui Leng, Hong‐jie Xu, Tian Lan, Dong‐lei Yan, Il‐keun Kong, Xian‐Feng Yu, Ming‐Jun Zhang, Yong‐Xun Jin   +14 more
wiley   +1 more source

Histological and ultrastructural analysis of cryopreserved sheep preantral follicles [PDF]

Animal Reproduction Science, 2006
The aim of this study was to verify the histological and ultrastructural characteristics of sheep preantral follicles after exposure of ovarian tissue to cryopreservation in glycerol (GLY), ethylene glycol (EG), propanediol (PROH) or dimethyl sulfoxide (DMSO) in order to determine the optimum method to store sheep ovarian tissue for later experimental ...
Santos, Regiane R., Rodrigues, Ana Paula Ribeiro, Costa, Sonia Helena Furtado, Silva, José Roberto Viana, Matosa, Maria H.T., Lucci, Carolina Madeira, Báo, Sônia Nair, Hurk, Rob Van Den, Figueiredo, José Ricardo de   +8 more
openaire   +3 more sources

Growth Differentiation Factor 9 Supplementation Restores the Lipopolysaccharide‐Induced Negative Effects on Bovine Oocyte Developmental Competence

Molecular Reproduction and Development, Volume 93, Issue 4, April 2026.
ABSTRACT Growth differentiation factor 9 (GDF9) plays a key role in enhancing developmental competence and blastocyst yield during in vitro maturation (IVM). This study investigated whether GDF9 could counteract the harmful effects of lipopolysaccharide (LPS), a gram‐negative bacterial component, on bovine in vitro embryo production, while also ...
Dragos Scarlet, Idil Serbetci, Gerhard Schuler, Heinrich Bollwein, Mariusz P. Kowalewski   +4 more
wiley   +1 more source

Morphological Study of Isolated Ovarian Preantral Follicles Using Fibrin Gel Plus Platelet Lysate after Subcutaneous Transplantation [PDF]

Cell Journal, 2015
Objective: Ovarian and follicle transplantation may preserve fertility in young cancer survivors. In this study, we have transplanted preantral follicles using fibrin gel as a carrier and fibrin gel supplemented with platelet lysate (PL) as a rich ...
Ali Reza Rajabzadeh, Hossein Eimani, Homa Mohseni Koochesfahani, Abdol-Hossein Shahvardi, Rouhollah Fathi   +4 more
doaj  

Immunolocalization for glucocorticoid receptor and effect of cortisol on in vitro development of preantral follicles

Veterinary and Animal Science, 2019
The aim of this study was to evaluate the immunolocalization for glucocorticoid receptor (NR3C1) in goat ovarian follicles and the effect of cortisol on in vitro development of preantral follicles.
Julian T. Pontes, Caroline Maside, Laritza F. Lima, Deborah M. Magalhães-Padilha, Rodrigo T. Padilha, Maria Helena T. Matos, José R. Figueiredo, Cláudio C. Campello   +7 more
doaj   +1 more source

Illustration of experimental procedures performed to assess the preantral follicle spatial distribution in the equine ovary.

, 2018
The ovaries were divided into (A) three portions (lateral, n = 2; intermediary, n = 1), followed by (B) histological processing. Thereafter, the main steps to guide the microscopy evaluation were performed: (C) squared sheet developed with columns and ...
Eduardo L. Gastal (2267074), Melba O. Gastal (2267056), José R. Figueiredo (2267077), Benner G. Alves (2267065), Kele A. Alves (2267062), Gustavo D. A. Gastal (2267071)   +5 more
core   +1 more source