Results 101 to 110 of about 90,880 (329)

Prebiotic effects: metabolic and health benefits [PDF]

open access: yes, 2010
The different compartments of the gastrointestinal tract are inhabited by populations of micro-organisms. By far the most important predominant populations are in the colon where a true symbiosis with the host exists that is a key for well-being and ...
Agnes Meheust   +94 more
core   +3 more sources

The Aging Gut–Brain Axis: Effects of Dietary Polyphenols and Metal Exposure

open access: yesChronic Diseases and Translational Medicine, EarlyView.
The influence of gut microbiota on brain health ABSTRACT Diet provides essential metals, which are required for the growth, development, and well‐functioning of the body. Nonetheless, some natural and human activities add toxic heavy metals to the diet, consequently introducing them to our bodies, resulting in several disorders and death. The intestine,
Luqi Cao   +7 more
wiley   +1 more source

Prebiotics in food and dietary supplements: a roadmap to EU health claims

open access: yesGut Microbes
Numerous studies have established that prebiotic ingredients in foods and dietary supplements may play a role in supporting human health. Over the three decades that have passed since prebiotics were first defined as a concept, research has revealed a ...
Kieran Tuohy   +21 more
doaj   +1 more source

Terahertz Raman Optical Activity Reveals Emergent Supramolecular Chirality in Mononucleotide G‐quadruplexes

open access: yesChemistry–Methods, EarlyView.
Self‐assembly of guanosine‐5′‐monophosphate into G‐quadruplexes induces a cation‐specific (sodium vs. potassium), intense terahertz Raman optical activity signal. The supramolecular helical arrangement gives rise to a distinct chiral vibrational signature in the low‐frequency region.
Štěpán Jílek   +2 more
wiley   +1 more source

Assessing the possibility of prevention, treatment and correction of the intestinal microflora dysbiotic disorders in experimental pseudotuberculosis

open access: yesЖурнал инфектологии, 2014
The possibility was studied of preventing the development of pseudotuberculosis and correcting the dysbiotic disorders of the intestinal microflora in conventional white mice with prebiotic «Stimbifid» and exometabolites in supernatant fluids of native ...
I. Yu. Chicherin   +4 more
doaj   +1 more source

Atomistic Modeling of Methyl Formate and Glycolaldehyde Formation on Interstellar Dirty Ice Mantles via a “Radical + Ice” Mechanism

open access: yesChemPlusChem, EarlyView.
The presence of interstellar complex organic molecules (COMs) has been baffling astrochemists for a long time. Methyl formate and glycolaldehyde are widely detected but their abundances mismatch kinetic astrochemical model predictions. Here, the formation of these two COMs is characterized onto a mixed ice surface, highlighting the importance of ...
Jessica Perrero   +3 more
wiley   +1 more source

Pharmacomicrobiomics

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Oral medications encounter gut commensal microbes that participate directly and indirectly in drug effects through metabolism, interactions with drug metabolites, or production of substrates that compete with drugs for drug‐metabolizing enzymes, consequently influencing drug pharmacokinetics.
Naomi Gronich   +11 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Reduced alphabet of prebiotic amino acids optimally encodes the conformational space of diverse extant protein folds

open access: yesBMC Evolutionary Biology, 2019
Background There is wide agreement that only a subset of the twenty standard amino acids existed prebiotically in sufficient concentrations to form functional polypeptides.
Armando D. Solis
doaj   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

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