Results 161 to 170 of about 60,622 (287)

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng   +6 more
wiley   +1 more source

Deciphering Branched Galactomannan Structures via Multistage Ion Mobility MS and MSn Fragmentation (Multistage IMSn)

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Hemicelluloses are abundant carbohydrate components in plant cell walls. They play a crucial structural role in binding cellulose microfibrils, in addition to other biological functions. Their high structural variability directly influences their biological properties, making it important to establish a structure–function ...
Rania Benazza   +3 more
wiley   +1 more source

Molecular Active Matter, Kinetic Asymmetry, and Non‐Reciprocal Interactions

open access: yesSmall, EarlyView.
Nanoscale enzymes constitute dissipative active matter that converts scalar energy input into vectorial outputs. Through kinetic and diffusion asymmetry, they break time and space symmetry, resulting in directional motion. This mechanism accounts for both positive and negative chemotaxis, as well as non‐reciprocal interactions between enzymes that ...
Niladri Sekhar Mandal   +3 more
wiley   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

open access: yesVIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

open access: yesVIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore   +5 more
wiley   +1 more source

Oral microbiome and homeostatic regulation of periodontal health: From dysbiosis to precision intervention

open access: yesVIEW, EarlyView.
Periodontal homeostasis is maintained by coordinated interactions between the oral microbiome and host. Dysbiosis disrupts this ecological balance and contributes to periodontal disease, whereas multi‐omics, artificial intelligence, and microbiome‐based interventions provide emerging opportunities for precision diagnosis, ecological restoration, and ...
Xu Liu   +11 more
wiley   +1 more source

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