Results 51 to 60 of about 19,936 (198)
Multiple prebiotic metals mediate translation. [PDF]
, 2018 Today, Mg2+ is an essential cofactor with diverse structural and functional roles in life's oldest macromolecular machine, the translation system. We tested whether ancient Earth conditions (low O2, high Fe2+, and high Mn2+) can revert the ribosome to a ...
Bowman, Jessica C +8 more
core +1 more source
Evolutionary Game-Theoretic Approach to the Population Dynamics of Early Replicators
LifeThe population dynamics of early replicators has revealed numerous puzzles, highlighting the difficulty of transitioning from simple template-directed replicating molecules to complex biological systems.
Matheus S. Mariano, José F. Fontanari
doaj +1 more source
Energetics in a model of prebiotic evolution
Physical Review E, 2017 Previously we reported [A. Wynveen et al., Phys. Rev. E 89, 022725 (2014)PLEEE81539-375510.1103/PhysRevE.89.022725] that requiring that the systems regarded as lifelike be out of chemical equilibrium in a model of abstracted polymers undergoing ligation and scission first introduced by Kauffman [S. A.
B F, Intoy, J W, Halley
openaire +3 more sources
Life, 2018 How life began on Earth is still largely shrouded in mystery. One of the central ideas for various origins of life scenarios is Darwin’s “warm little pond„. In these small bodies of water, simple prebiotic compounds such as amino acids,
Jeffrey L. Bada, Jun Korenaga
doaj +1 more source
Prebiotic evolution: Selecting for homochirality before RNA [PDF]
Current Biology, 1997 Recent results show that the self-assembly of long homochiral oligomers of a nucleotide analogue can be achieved by ligation of short oligomers of chirally mixed composition. Do these results show how the RNA world might have arisen?
openaire +3 more sources
Toward stable replication of genomic information in pools of RNA molecules
eLifeThe transition from prebiotic chemistry to living systems requires the emergence of a scheme for enzyme-free genetic replication. Here, we analyze a recently proposed prebiotic replication scenario, the so-called Virtual Circular Genome (VCG) [Zhou et al.
Ludwig Burger, Ulrich Gerland
doaj +1 more source
From Cosmos to Intelligent Life: The Four Ages of Astrobiology
, 2012 The history of life on Earth and in other potential life-bearing planetary platforms is deeply linked to the history of the universe. Since life as we know it relies on chemical elements forged in dying heavy stars, the universe needs to be old enough ...
Abel +17 more
core +1 more source
Boron enrichment in Martian clay [PDF]
, 2013 We have detected a concentration of boron in martian clay far in excess of that in any previously reported extra-terrestrial object. This enrichment indicates that the chemistry necessary for the formation of ribose, a key component of RNA, could have ...
Freeland, Stephen J. +4 more
core +3 more sources
Motility at the origin of life: Its characterization and a model
, 2013 Due to recent advances in synthetic biology and artificial life, the origin of life is currently a hot topic of research. We review the literature and argue that the two traditionally competing "replicator-first" and "metabolism-first" approaches are ...
Froese, Tom +2 more
core +1 more source
Selection of Prebiotic Molecules in Amphiphilic Environments
Life, 2017 A basic problem in all postulated pathways of prebiotic chemistry is the low concentration which generally is expected for interesting reactants in fluid environments.
Christian Mayer +2 more
doaj +1 more source