Results 11 to 20 of about 47,171 (271)

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Effect of misoprostol on type 3 transformation zone of the cervix among Cameroonian women

Gynecologic Oncology Reports, 2022
Background: Type 3 transformation zone (TZ) of the cervix has been shown to be associated with a four to five-fold increased risk of missed precancerous/cancerous lesions.
Simon M. Manga, Margaret I. Liang, Yuanfan Ye, Jeff M. Szychowski, Kathleen L. Nulah, Alan T. Tita, Isabel Scarinci, Warner K. Huh   +7 more
doaj   +1 more source

Angiogenesis in squamous precancerous cervical lesions [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. Vascularisation is one of basic tumor's characteristics. Neoangiogenesis starts at the stage of the dysplastic epithelial changes, thus before the progression into invasive lesion. This study was designed to determine the relation between
Panjković Milan, Ivković-Kapicl Tatjana   +1 more
doaj   +1 more source

Awareness of patients about existing oral precancerous lesions/conditions in Nashik city of Maharashtra

Journal of Indian Association of Public Health Dentistry, 2016
Introduction: Many oral squamous cell carcinomas develop from premalignant lesions/conditions of oral cavity. Hence, the awareness of such lesions/conditions is important.
Bhushan Sukdeo Ahire, Ajay R Bhoosreddy, Seema A Bhoosreddy, Atul Ashok Pandharbale, Varun R Kunte, Manila R Shinde   +5 more
doaj   +1 more source

Verrucous leukoplakia of the red border caused by the use of IQOS heated tobacco product (a case report)

Zaporožskij Medicinskij Žurnal, 2020
The aim. To analyze possibility of development and describe the clinical case of the red border verrucous leukoplakia caused by the use of IQOS heated tobacco product and HEETS sticks and propose personalized clinical, diagnostic and therapeutic ...
H. I. Makurina, O. I. Мakarchuk, I. P. Dmytrenko, A. V. Holovkin, I. А. Sokolovska, A. S. Chornenka   +5 more
doaj   +1 more source

Radiotherapy treatment of the common Keira's erythroplasia form

Вестник урологии, 2021
Bowen's disease, Keira's erythroplasia and bowenoid papulosis are currently classified as precancerous penis lesions associated with human papillomavirus (HPV). The diagnosis and treatment of precancerous penis lesions is a unique challenge.
F. R. Dzhabarov, A. B. Alnikin, V. G. Tolmachev   +2 more
doaj   +1 more source

Research Progress on Cancer Risk and Its Pathogenesis of Gastric Precancerous Conditions [PDF]

Zhongguo quanke yixue
The gastric precancerous conditions includes gastric mucosal atrophy and intestinal metaplasia, which is key link in the occurrence and development of gastric cancer, and its prevalence is on the rise in China.
WANG Yuxin, PENG Wenwan, ZHOU Zheng, HUANG Haiyang, LU Xiaomin, DONG Mingguo
doaj   +1 more source

The molecular landscape of colitis-associated carcinogenesis [PDF]

, 2016
In spite of the well-established histopathological phenotyping of IBD-associated preneoplastic and neoplastic lesions, their molecular landscape remains to be fully elucidated. Several studies have pinpointed the initiating role of longstanding/relapsing
D'Inca', Renata, Fassan, Matteo, Mescoli, Claudia, Michielan, Andrea, Rugge, Massimo, Saraggi, Deborah, Scarpa, Marco, Valeri, Nicola   +7 more
core   +1 more source

Ultrasound criteria for predicting pre-cancer changes of the gastric mucosa in patients with chronic atrophic gastritis combined with thyroid pathology

Zaporožskij Medicinskij Žurnal, 2022
Precancerous conditions increase the risk of gastric cancer by 2–3 % every 10 years. Among comorbid pathology, 46 % of all endocrinopathies are diseases of the thyroid gland.
Yu. M. Stepanov, L. M. Mosiichuk, I. S. Konenko, O. V. Simonova, O. P. Petishko, O. M. Shevtsova, L. V. Demeshkina   +6 more
doaj   +1 more source

Clinical and histopathological study of actinic cheilitis

Revista de Odontologia da UNESP, 2019
Introduction Actinic cheilitis is a inflammatory condition affecting mainly the lower lip and it is caused by chronic and excessive exposure of the lips to the ultraviolet radiation in sunlight.
Lívia Natália Sales BRITO, Antônio Carlos Evangelista da Araújo BONFIM, Daliana Queiroga de Castro GOMES, Pollianna Muniz ALVES, Cassiano Francisco Weege NONAKA, Gustavo Pina GODOY   +5 more
doaj   +1 more source