Results 31 to 40 of about 8,350,584 (283)

Plasma cell-free RNA profiling distinguishes cancers from pre-malignant conditions in solid and hematologic malignancies

npj Precision Oncology, 2022
Cell-free RNA (cfRNA) in plasma reflects phenotypic alterations of both localized sites of cancer and the systemic host response. Here we report that cfRNA sequencing enables the discovery of messenger RNA (mRNA) biomarkers in plasma with the tissue of ...
Breeshey Roskams-Hieter, Hyun Ji Kim, Pavana Anur, Josiah T. Wagner, Rowan Callahan, Elias Spiliotopoulos, Charles Ward Kirschbaum, Fehmi Civitci, Paul T. Spellman, Reid F. Thompson, Khashayar Farsad, Willscott E. Naugler, Thuy T. M. Ngo   +12 more
doaj   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Angiogenesis in squamous precancerous cervical lesions [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. Vascularisation is one of basic tumor's characteristics. Neoangiogenesis starts at the stage of the dysplastic epithelial changes, thus before the progression into invasive lesion. This study was designed to determine the relation between
Panjković Milan, Ivković-Kapicl Tatjana   +1 more
doaj   +1 more source

Research Progress on Cancer Risk and Its Pathogenesis of Gastric Precancerous Conditions [PDF]

Zhongguo quanke yixue
The gastric precancerous conditions includes gastric mucosal atrophy and intestinal metaplasia, which is key link in the occurrence and development of gastric cancer, and its prevalence is on the rise in China.
WANG Yuxin, PENG Wenwan, ZHOU Zheng, HUANG Haiyang, LU Xiaomin, DONG Mingguo
doaj   +1 more source

Is Nodular Gastritis a Precancerous Condition? [PDF]

Digestive Diseases and Sciences, 2012
I read with great interest the article by Hong et al. [1]. They analyzed clinico-epidemiological characteristics of 52 patients with nodular gastritis (NG) and 2,527 controls. Gastric neoplasm was detected in a single patient in the NG group (1.9 %) and in five patients in the control group (0.2 %).
openaire   +4 more sources

Clinical and histopathological study of actinic cheilitis

Revista de Odontologia da UNESP, 2019
Introduction Actinic cheilitis is a inflammatory condition affecting mainly the lower lip and it is caused by chronic and excessive exposure of the lips to the ultraviolet radiation in sunlight.
Lívia Natália Sales BRITO, Antônio Carlos Evangelista da Araújo BONFIM, Daliana Queiroga de Castro GOMES, Pollianna Muniz ALVES, Cassiano Francisco Weege NONAKA, Gustavo Pina GODOY   +5 more
doaj   +1 more source

Serum Iron and Haemoglobin Estimation in Oral Submucous Fibrosis and Iron Deficiency Anaemia: A Diagnostic Approach [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Oral Submucous Fibrosis (OSMF) is a premalignant condition with potential malignant behaviour characterized by juxta-epithelial fibrosis of the oral cavity.
Divya Bhardwaj, Ajit D Dinkar, Sujata K Satoskar, Sapna Raut Desai   +3 more
doaj   +1 more source

Stability analysis of an age-structured model of cervical cancer cells and HPV dynamics

Mathematical Biosciences and Engineering, 2021
Stability analysis of an autonomous epidemic model of an age-structured sub-populations of susceptible, infected, precancerous and cancer cells and unstructured sub-population of human papilloma virus (HPV) (SIPCV epidemic model) aims to gain an insight ...
Vitalii V. Akimenko, Fajar Adi-Kusumo
doaj   +1 more source

Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideli

Endoscopy, 2019
Patients with chronic atrophic gastritis or intestinal metaplasia (IM) are at risk for gastric adenocarcinoma. This underscores the importance of diagnosis and risk stratification for these patients. High definition endoscopy with chromoendoscopy (CE) is
P. Pimentel-Nunes, D. Libânio, R. Marcos-Pinto, M. Areia, M. Leja, G. Esposito, M. Garrido, I. Ķikuste, F. Mégraud, T. Matysiak-Budnik, B. Annibale, J. Dumonceau, R. Barros, J. Fléjou, F. Carneiro, J. V. van Hooft, E. Kuipers, M. Dinis-Ribeiro   +17 more
semanticscholar   +1 more source

New Insights Into the Role of Tissue Eosinophils in the Progression of Colorectal Cancer: A Literature Review

Acta Médica Portuguesa, 2018
Introduction: Amongst the inflammatory cells implicated in the immune surveillance of colorectal cancer, a growing body of evidence suggests a role for eosinophils in carcinogenesis.
Ana Laura Saraiva, Fátima Carneiro
doaj   +1 more source