A tug-of-war between driver and passenger mutations in cancer and other adaptive processes [PDF]
Cancer progression is an example of a rapid adaptive process where evolving new traits is essential for survival and requires a high mutation rate. Precancerous cells acquire a few key mutations that drive rapid population growth and carcinogenesis ...
Korolev, Kirill S.+2 more
core +2 more sources
Effect of probiotics on the development of dimethylhydrazine-induced preneoplastic lesions in the mice colon [PDF]
PURPOSE: To determine the effect of probiotics on the development of chemically induced (1, 2-dimethylhydrazine) colonic preneoplastic lesions, in mice. METHODS: The animals were divided into five groups.
Juliana Costa Liboredo+6 more
doaj +3 more sources
Efficacy of Oil Pulling in the Management of Oral Submucous Fibrosis: A Preliminary Study
Objective: To evaluate the effectiveness of oil pulling in the management of oral submucous fibrosis (OSMF). Material and Methods: A total of 62 patients clinically and histopathologically diagnosed as OSMF were incorporated in the present study.
Swatantra Shrivastava+6 more
doaj
Use of defatted flaxseed meal reduces precancerous colon lesions in C57BL/6 mice [PDF]
PURPOSE: To investigate the hemopreventive effect of defatted flaxseed meal in C57BL/6 mice after induction of precancerous colon lesions with 1.2-dimethylhydrazine (DMH).
Antônio Frederico de Freitas Gomides+5 more
doaj +1 more source
Treatment of helicobacter pylori infection in atrophic gastritis [PDF]
Helicobacter pylori (Hp) is a major human pathogen causing chronic, progressive gastric mucosal damage and is linked to gastric atrophy and cancer. Hp-positive individuals constitute the major reservoir for transmission of infection.
Annibale, B, Carabotti, M, Lahner, E
core +1 more source
Precancerous conditions increase the risk of gastric cancer by 2–3 % every 10 years. Among comorbid pathology, 46 % of all endocrinopathies are diseases of the thyroid gland.
Yu. M. Stepanov+6 more
doaj +1 more source
What’s hidden under the gastric intestinal metaplasia? Diffuse-type adenocarcinoma dscovered by targeted biopsies: a case-report [PDF]
Gastric corpus atrophy and intestinal metaplasia are two well established gastric precancerous conditions and scientific evidence shows a confidential relationship between this precancerous condition and intestinal type gastric cancer, according to ...
Angeletti Stefano+5 more
core +1 more source
Effect of misoprostol on type 3 transformation zone of the cervix among Cameroonian women
Background: Type 3 transformation zone (TZ) of the cervix has been shown to be associated with a four to five-fold increased risk of missed precancerous/cancerous lesions.
Simon M. Manga+7 more
doaj
In this case report, we present the radiologic and pathologic findings of atypical ductal hyperplasia (ADH) in the male breast. It is well known that a high-risk lesion such as ADH is a precursor of breast cancer in females.
Ara Ko+5 more
doaj +1 more source
Qualitative Evaluation of ‘BIPP Dressing’ for Intraoral Mucosal Defect [PDF]
Introduction: Various biologic and non biologic graft materials are considered in the past as Intraoral wound dressing material. While autografts have issues related to donor site morbidity, allografts like collagen have limited intraoral usage due to ...
Arun Paul Charlu+2 more
doaj +1 more source