Results 121 to 130 of about 63,378 (243)

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 41, 6 November 2026.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, Volume 13, Issue 63, 12 November 2026.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu   +6 more
wiley   +1 more source

Mechanical and Durability Performance of Concrete Incorporating Shredded Waste Polyethylene Terephthalate (PET) as Partial Fine Aggregate Replacement

open access: yesEngineering Reports, Volume 8, Issue 11, November 2026.
Incorporating shredded waste PET as a partial fine aggregate replacement up to 20%$$ 20\% $$ in C‐25 concrete provides a sustainable recycling solution, maintaining low water permeability and acceptable structural strength across all tested replacement levels. ABSTRACT The growing demand for concrete has increased the consumption of natural sand, while
Yeabsra Mulugeta Alamir   +4 more
wiley   +1 more source

Sustainable and Seismically Resilient Confined Masonry: Global Progress in Research and Design Practice

open access: yesEarthquake Spectra, Volume 42, Issue 4, November 2026.
Modern confined masonry (CM) construction consists of masonry walls confined by reinforced concrete (RC) tie‐columns and tie‐beams. When built correctly, CM buildings have shown good performance in earthquake's shaking. Even though CM construction has been practised for almost a century in some Latin American countries, its use and standardisation are ...
Ahsana Parammal Vatteri   +23 more
wiley   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

open access: yesGlia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy