Results 61 to 70 of about 25,298 (300)

Marketing madness

Voices in Bioethics, 2020
I.               Introduction In Sorrell v. IMS Health, the Supreme Court struck down a Vermont regulation requiring pharmacies to obtain prescriber consent to release prescriber-identifying information[1] to data miners for marketing research purposes.
Anne Zimmerman
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Structure and Precedent

, 2010
The standard model of vertical precedent is part of the deep structure of our legal system. Under this model, we rarely struggle with whether a given decision of a court within a particular hierarchy is potentially binding at all.
Dobbins, Jeffrey C.
core  

Vigilante grocers

Voices in Bioethics, 2020
A.      Introduction Before the COVID-19 pandemic, the protection of consumer privacy had reached a milestone with the enactment of the California Consumer Privacy Act (CCPA).[i] Stores that screen customers for elevated temperatures challenge the ...
Anne Zimmerman
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Have the High Court of Australia’s Directions in Farah Constructions Regarding “Seriously Considered Dicta” Needlessly Undermined the Doctrine of Precedent and Legal Certainty?

In the 2007 decision in Farah Constructions Pty Ltd v Say-Dee Pty Ltd, the High Court of Australia criticized the New South Wales Court of Appeal’s recognition of a new cause of action as inappropriate since it departed from “long-established authority ...
DENG, Haodi
core   +1 more source

Comparative Analysis of the Functioning of Prepositions / Postpositions and Conjunctions as Means of Expressing the Category of Precedence in the Tatar and Russian Languages

Polylinguality and Transcultural Practices
This article presents a semantic-syntactic analysis of prepositions / postpositions and conjunctions of the Tatar and Russian languages with the semantics of precedence.
Gulnara F. Lutfullina
doaj   +1 more source

من الأساليب التعليمـة المستخـدمـة فـي بيان النبـوة دراسـة بـلاغيـة (A Rhetorical Study of the Educational Methods Used in Explaining Prophethood) [PDF]

Maǧallaẗ Kulliyyaẗ al-Luġaẗ al-'arabiyyaẗ bi-Assiut
    المتأمل في أحاديث النبي  r يجد أنها اشتملت على أساليب تربوية عالية صاغها النبي -r- صياغة بلاغية عالية، ومن هذه الأساليب التربوية  الأساليب التعليمية التي وظفها النبي- r- في مواقف متعددة لأغراض مختلفة، حيث كان يراعي أحوال المخاطبين في كلامه، ويختار ...
محمد شاكر محمد صهوان
doaj   +1 more source