Results 81 to 90 of about 25,298 (300)

CRISPR-Cas9 Genomic Editing is an Ethical Frontier: Insert…Backspace…Delete… Fix Typo…Cure Disease

open access: yesVoices in Bioethics, 2016
On February 1st, 2016, a team of scientists at the Francis Crick Institute received approval from the UK Human Fertilization and Embryology Authority (HFEA) to use CRISPR-Cas9 to edit the genetic makeup of human embryos.[1] This monumental “first” in ...
Andrew Hawkins
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Consensus statement on an updated core communication curriculum for UK undergraduate medical education [PDF]

open access: yes, 2018
Objectives Clinical communication is a core component of undergraduate medical training. A consensus statement on the essential elements of the communication curriculum was co-produced in 2008 by the communication leads of UK medical schools.
Wesley Scott-Smith (16222190)   +3 more
core   +2 more sources

Texas House Bill 2

open access: yesVoices in Bioethics, 2015
In 1992, the United States Supreme Court, in Planned Parenthood of Southeastern Pennsylvania v. Casey, upheld the ruling in Roe v. Wade, namely that women have a right “to choose to have an abortion before viability and to obtain it without undue ...
Rachel Hill
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

AN UPHILL BATTLE FOR REPARATIONISTS

open access: yesColumbia Journal of Race and Law, 2020
On Juneteenth (June 19), 2019 the United States House Judiciary Committee heard over three hours of testimony regarding slavery reparations.[1]  Various rhetorical methods were used by the expert witnesses to promote slavery reparations.  Many emphasized
Michael Conklin
doaj  

An Analysis of New York State's Medical Aid in Dying Act (A. 2383A S. 3151)

open access: yesVoices in Bioethics, 2018
Introduction An amended version of the proposed Medical Aid in Dying Act (A. 2383A S. 3151) was recently filed with the New York State legislature [1].
Michael Dauber
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Alberto F. Garay. La doctrina del precedente en la Corte Suprema. Abeledo Perrot, 2013. Pp. 417. Price: ARS 862. ISBN: 9789502025100

open access: yes, 2017
In his foreword to La doctrina del precedente en la Corte Suprema, Alejandro Garro, an Argentine academic who teaches at Columbia Law School in New York, claims that this monograph by Alberto F.
Legarre, Santiago, Santiago Legarre
core   +1 more source

PRECEDENT NAMES AND STATEMENTS IN FOREIGN LANGUAGE DISCOURSE

open access: yesHumanities science current issues, 2023
Oksana NAIDIUK, Viktoriia PRYKHODKO
openaire   +1 more source

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