Results 111 to 120 of about 47,692 (297)

Extended Anionic Network in Mixed‐Valent Nitridocobaltates(I/II) LnCo2N2 (Ln = La, Pr, Nd)

open access: yesAdvanced Science, EarlyView.
This study presents the high‐pressure synthesis of LnCo2N2 (Ln = La, Pr, Nd) with Co in mixed valent states of +I/+II. The compounds demonstrate the stabilization of a nitridocobaltate with extended anionic Co–N layers where Co is threefold coordinated.
Nina A. M. Prinz   +5 more
wiley   +1 more source

PRECEDENTES REAIS, GERENCIAIS E DECISÕES DE APLICAÇÃO

open access: yesBrazilian Journal of Empirical Legal Studies
Este artigo propõe uma tipologia das decisões judiciais em geral, olhando especificamente para o caso do Supremo Tribunal Federal, com o objetivo de clarificar o conteúdo do direito revelado através da jurisprudência.
José Luiz Nunes   +1 more
doaj   +1 more source

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

open access: yesAdvanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang   +6 more
wiley   +1 more source

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu   +11 more
wiley   +1 more source

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

open access: yesAdvanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan   +5 more
wiley   +1 more source

Os precedentes judiciais no sistema arbitral brasileiro [PDF]

open access: yes, 2018
Orientador: Paulo Roberto Ribeiro NalinMonografia (Graduação) - Universidade Federal do Paraná, Setor de Ciências Jurídicas, Curso de Graduação em DireitoResumo: O presente trabalho trata da aplicação dos precedentes judiciais no sistema arbitral.
Menin, Leonardo Catto, 1994-
core  

Unraveling Hierarchical B‐Site Ordering: Mechanism of Microwave Dielectric Enhancement in Complex Perovskite Oxide Ceramics

open access: yesAdvanced Science, EarlyView.
This study maps out the hierarchical ordering in 1:2 B‐site complex perovskite ceramics using a comprehensive multiscale characterization route. It turns out that intradomain strain, oxygen vacancies, and Mg disorder within the ordered domains act as strong phonon scatterers.
Qingqiao Fu   +6 more
wiley   +1 more source

REFLEXÃO ACERCA DA APLICAÇÃO DOS PRECEDENTES JUDICIAIS [PDF]

open access: yes, 2018
O presente trabalho possui o objetivo de analisar os precedentes judiciais através de um aspecto negativo, isto é, refletir acerca dos impactos prejudiciais da utilização dos precedentes nos processos judiciais.
Franche, Suzan Raphaellen
core  

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

open access: yesAdvanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu   +12 more
wiley   +1 more source

Reforma no processo trabalhista brasileiro em direção aos precedentes obrigatórios: a Lei n. 13.015/2014 [PDF]

open access: yes, 2014
Em 22 de julho de 2014 foi publicada a Lei n. 13.015, já regulamentada pela Resolução n. 1.699 do TST, que reformou o processo do trabalho, trazendo novidades de extrema relevância que não podem ser tratadas apressadamente.
Macêdo, Lucas Buril de   +1 more
core  

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