Results 221 to 230 of about 102,033 (344)
Coupled Above‐ and Belowground Ecosystem Stability Worldwide
Are the worlds above and below our feet in sync? This global exploration reveals an entangled fate between above‐ and belowground ecosystem stability. It identifies arid regions as hotspots for this coupling and highlights temperature stability as a vital safeguard for maintaining ecosystem balance across our warming planet.
Zexin Meng +18 more
wiley +1 more source
Tailoring the Mechanical Properties of Al<sub>0.4</sub>CrFe<sub>2</sub>Ni<sub>2</sub> Medium-Entropy Alloy via Thermomechanical Processing. [PDF]
Kočiško R +7 more
europepmc +1 more source
NIBAN2/FLII/RREB1 Axis Drives Glioma Stem Cell Malignancy via TLR3 Pathway Activation
NIBAN2, highly expressed in glioma stem‐like cells (GSCs), assembles with FLII and transcription factor RREB1 to form a nuclear complex. This complex transcriptionally activates stemness‐associated genes (e.g., CD44, NANOG) and metabolic enzymes (e.g., LDHA), thereby sustaining both transcriptional and metabolic stemness programs.
Liang liang Shi +14 more
wiley +1 more source
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang +16 more
wiley +1 more source
Refining the Carbide Size in AISI M50 High-Speed Steel Through Tailored Compositional Modifications. [PDF]
Yang P, Xie X, Yang C, Hui X, Liu T.
europepmc +1 more source
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao +12 more
wiley +1 more source
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source

