Results 71 to 80 of about 602,455 (339)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
A More Reliable Orbit Initialization Method for LEO Precise Orbit Determination Using GNSS
Remote Sensing, 2020 Precise orbit determination (POD) using GNSS has been rapidly developed and is the mainstream technology for the navigation of low Earth orbit (LEO) satellites. The initialization of orbit parameters is a key prerequisite for LEO POD processing.
Xuewen Gong +3 more
doaj +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
COSMIC-2 Precise Orbit Determination [PDF]
, 2019 We present initial results for post-processed GNSS orbit and clock estimation for the FORMOSAT-7/COSMIC-2 (Constellation Observing System for Meteorology, Ionosphere, and Climate) constellation.
Arnold, Daniel +5 more
core
FEBS Letters, EarlyView.LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra +7 more
wiley +1 more source
Radio detection of the young binary HD 160934 [PDF]
, 2013 Precise determination of dynamical masses of pre-main-sequence (PMS) stars is essential to calibrate stellar evolution models that are widely used to derive theoretical masses of young low-mass objects. Binary stars in young, nearby loose associations are particularly good candidates for this calibration since all members share a common age ...
arxiv +1 more source
New Precision Orbits of Bright Double-Lined Spectroscopic Binaries. I: RR Lyncis, 12 Bootis, and HR 6169 [PDF]
Astron.J.131:2652-2663,2006, 2006 Radial velocities from the 2.1 m telescope at McDonald Observatory supplemented with radial velocities from the coude' feed telescope at KPNO provide new precise orbits for the double-lined spectroscopic binaries RR Lyn (A3/A8/A6), 12 Boo (F8IV), and HR 6169 (A2V). We derive orbital dimensions and minimum masses with accuracies of 0.06 to 0.9 %.
arxiv +1 more source
FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
Weighing the Darkness: Astrometric Mass Measurement of Hidden Stellar Companions using Gaia [PDF]
, 2019 In astrometric binaries, the presence of a dark, unseen star can be inferred from the gravitational pull it induces on its luminous binary companion. While the orbit of such binaries can be characterized with precise astrometric measurements, constraints made from astrometry alone are not enough to measure the component masses.
arxiv +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source