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Polypharmacy and precision medicine
Precision medicine is an approach to maximise the effectiveness of disease treatment and prevention and minimise harm from medications by considering relevant demographic, clinical, genomic and environmental factors in making treatment decisions ...
Kenji Fujita+4 more
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Precision regenerative medicine [PDF]
Background Precision or individualized medicine is increasingly pervasive across medical and surgical disciplines. However, the concept has not been introduced in regenerative medicine.
Amy L. Lightner, Timothy Chan
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Precision mitochondrial medicine
Mitochondria play a key role in cell homeostasis as a major source of intracellular energy (adenosine triphosphate), and as metabolic hubs regulating many canonical cell processes.
Patrick F. Chinnery
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Clinical management of metastatic colorectal cancer in the era of precision medicine
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second most common cause of cancer deaths. Initial clinical presentation as metastatic CRC (mCRC) occurs in approximately 20% of patients. Moreover, up to 50% of patients with
Fortunato Ciardiello+2 more
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Radiotheranostics in oncology: Making precision medicine possible
A quintessential setting for precision medicine, theranostics refers to a rapidly evolving field of medicine in which disease is diagnosed followed by treatment of disease‐positive patients using tools for the therapy identical or similar to those used ...
Eric O Aboagye
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Precision Chemistry for Precision Medicine
During the 2015 State of the Union address, President Obama unveiled plans for a $215 million Precision Medicine Initiative. The details of this plan were laid out by past and present directors of the National Institutes of Health, Harold Varmus and Francis Collins, in a commentary in the New England Journal of Medicine.1 While the announcement stood ...
George M. Church
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The Affordable Care Act (ACA) has continued to transform the health care system that provides men’s health care services. ACA has proposed a patient-centered, safe, quality initiative that embraces transparency from the funding of health care services to the provision of services.
Demetrius J. Porche DNS, PhD, FAANP, FAAN
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Precision Medicine: The new era in medicine [PDF]
Precision medicine, also known as stratified medicine or personalized medicine, aims to better target intervention to the individual, maximize benefit and minimize harm. Enthusiasm for the prospect of precision medicine has grown significantly in the last few years. There has been increasing interest in two streams of development in precision medicine.
Marinka Twilt
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Precision medicine at the crossroads [PDF]
There are bioethical, institutional, economic, legal, and cultural obstacles to creating the robust-precompetitive-data resource that will be required to advance the vision of “precision medicine,” the ability to use molecular data to target therapies to
Maynard V. Olson
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