Results 41 to 50 of about 1,197,472 (281)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior +7 more
wiley +1 more source
The Master Observational Trial: A New Class of Master Protocol to Advance Precision Medicine. [PDF]
, 2020 This commentary introduces a new clinical trial construct, the Master Observational Trial (MOT), which hybridizes the power of molecularly based master interventional protocols with the breadth of real-world data.
Bergan, Raymond +5 more
core
Genetics update: monogenetics, polygene disorders and the quest for modifying genes [PDF]
, 2018 The genetic channelopathies are a broad collection of diseases. Many ion channel genes demonstrate wide phenotypic pleiotropy, but nonetheless concerted efforts have been made to characterise genotype-phenotype relationships.
Symonds, Joseph D., Zuberi, Sameer M.
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim +8 more
wiley +1 more source
Integrating biomedical research and electronic health records to create knowledge-based biologically meaningful machine-readable embeddings. [PDF]
, 2019 In order to advance precision medicine, detailed clinical features ought to be described in a way that leverages current knowledge. Although data collected from biomedical research is expanding at an almost exponential rate, our ability to transform that
Baranzini, Sergio E +2 more
core
Integrative methods for analyzing big data in precision medicine [PDF]
, 2015 We provide an overview of recent developments in big data analyses in the context of precision medicine and health informatics. With the advance in technologies capturing molecular and medical data, we entered the area of “Big Data” in biology and ...
Gligorijević, V +2 more
core +1 more source
Precision mitochondrial medicine
Cambridge Prisms: Precision Medicine, 2022 Abstract Mitochondria play a key role in cell homeostasis as a major source of intracellular energy (adenosine triphosphate), and as metabolic hubs regulating many canonical cell processes. Mitochondrial dysfunction has been widely documented in many common diseases, and genetic studies point towards a causal role in the pathogenesis ...
openaire +3 more sources
Xin yixueObesity has become a critical public-health issue compromising the health of Chinese residents, and in 2024 the National Health Commission issued the Implementation Plan for the “Weight-Management Year” Initiative, launching a three-year campaign that ...
Guideline Compilation Group of the Weight Management Branch of the Guangdong Precision Medicine Application Association
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source