Results 51 to 60 of about 5,006,360 (256)
Xin yixueObesity has become a critical public-health issue compromising the health of Chinese residents, and in 2024 the National Health Commission issued the Implementation Plan for the “Weight-Management Year” Initiative, launching a three-year campaign that ...
Guideline Compilation Group of the Weight Management Branch of the Guangdong Precision Medicine Application Association
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Precision Medicine in Systemic Mastocytosis
Medicina, 2021 Mastocytosis is a rare hematological neoplasm characterized by the proliferation of abnormal clonal mast cells (MCs) in different cutaneous and extracutaneous organs.
Maura Nicolosi +7 more
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The problematic side of precision medicine
, 2022 Adopting the US National Research Council definition of ‘precision medicine’, I present some of the main quandaries posed by this approach to biomedical research and clinical practice.
G. Boniolo
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim +11 more
wiley +1 more source
Nanoplasmonic biosensors for precision medicine
Frontiers in Chemistry, 2023 Nanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic
Yiran Xiao +5 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Precision Medicine for Lysosomal Disorders
Biomolecules, 2020 Precision medicine (PM) is an emerging approach for disease treatment and prevention that accounts for the individual variability in the genes, environment, and lifestyle of each person. Lysosomal diseases (LDs) are a group of genetic metabolic disorders
Filippo Pinto e Vairo +6 more
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Precision medicine in mood disorders
PCN Reports, 2022 The choice of the most appropriate psychoactive medication for each of our patients is always a challenge. We can use more than 100 psychoactive drugs in the treatment of mood disorders, which can be prescribed either alone or in combination.
Alessandro Serretti
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Conducting Precision Medicine Research with African Americans. [PDF]
, 2016 Precision medicine is an approach to detecting, treating, and managing disease that is based on individual variation in genetic, environmental, and lifestyle factors.
Melanie Jefferson (3149163) +14 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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