Results 51 to 60 of about 1,197,472 (281)

Precision Medicine in Systemic Mastocytosis

Medicina, 2021
Mastocytosis is a rare hematological neoplasm characterized by the proliferation of abnormal clonal mast cells (MCs) in different cutaneous and extracutaneous organs.
Maura Nicolosi, Andrea Patriarca, Annalisa Andorno, Abdurraouf Mokhtar Mahmoud, Alessandra Gennari, Renzo Boldorini, Gianluca Gaidano, Elena Crisà   +7 more
doaj   +1 more source

SUBIC: A Supervised Bi-Clustering Approach for Precision Medicine

, 2017
Traditional medicine typically applies one-size-fits-all treatment for the entire patient population whereas precision medicine develops tailored treatment schemes for different patient subgroups.
Levy, Phillip, Nezhad, Milad Zafar, Sadati, Najibesadat, Yang, Kai, Zhu, Dongxiao   +4 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Nanoplasmonic biosensors for precision medicine

Frontiers in Chemistry, 2023
Nanoplasmonic biosensors have a huge boost for precision medicine, which allows doctors to better understand diseases at the molecular level and to improve the earlier diagnosis and develop treatment programs. Unlike traditional biosensors, nanoplasmonic
Yiran Xiao, Zongming Zhang, Shi Yin, Xingyi Ma, Xingyi Ma, Xingyi Ma   +5 more
doaj   +1 more source

SAFS: A Deep Feature Selection Approach for Precision Medicine

, 2017
In this paper, we propose a new deep feature selection method based on deep architecture. Our method uses stacked auto-encoders for feature representation in higher-level abstraction.
Levy, Phillip, Li, Xiangrui, Nezhad, Milad Zafar, Yang, Kai, Zhu, Dongxiao   +4 more
core   +1 more source

Improving Community Advisory Board Engagement In Precision Medicine Research To Reduce Health Disparities [PDF]

, 2020
Community Advisory Boards (CABs) are used in efforts to reduce health disparities; however, there is little documentation in the literature regarding their use in precision medicine research.
Adams, Marilyn, Barlow, Calvin, Canedo, Juan, Connors, Erin, Cox, Nora, Fadden, Mary Kay, Gilliam, Karen, Hull, Pamela, Johns-Porter, Denice, King, Stephen, McAfee, Caree, McDermott, Ila, Miller, Oscar, Sanderson, Maureen, Selove, Rebecca, Tindle, Hilary   +15 more
core   +2 more sources

MicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine. [PDF]

, 2017
The high degree of conservation in microRNA from Caenorhabditiselegans to humans has enabled relatively rapid implementation of findings in model systems to the clinic.
Agarwal, Priyanka, Bhowmick, Neil A, Smith, Bethany   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Precision medicine and traditional chinese medicine of dialogue

BIO Web of Conferences, 2017
The precision medicine is more precise individualized medicine, based on the patient’s genes or physiological to formulate the specific treatment plan, for the realization of individualized treatment of various diseases to provide valuable information ...
Lou Xin, Bai Ming, Miao Mingsan
doaj   +1 more source

Precision Medicine for Frontotemporal Dementia

Frontiers in Psychiatry, 2019
Frontotemporal dementia (FTD) is a common young-onset dementia presenting with heterogeneous and distinct syndromes. It is characterized by progressive deficits in behavior, language, and executive function.
Mu-N Liu, Mu-N Liu, Mu-N Liu, Chi-Ieong Lau, Chi-Ieong Lau, Chi-Ieong Lau, Ching-Po Lin, Ching-Po Lin, Ching-Po Lin   +8 more
doaj   +1 more source