Results 31 to 40 of about 648,115 (257)

Rationale and design of the Kidney Precision Medicine Project.

, 2021
Chronic kidney disease (CKD) and acute kidney injury (AKI) are common, heterogeneous, and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate a precision-medicine approach to prevention, diagnosis, and treatment.
Tuttle, Katherine, Kidney Precision Medicine Project,, El-Achkar, Tarek M, de Boer, Ian H., Troyanskaya, Olga G., Vazquez, Miguel A., Palevsky, Paul M, Gaut, Joseph P., Azeloglu, Evren U, Hodgin, Jeffrey B, Toto, Robert D., Eadon, Michael T, O\u27Toole, John F, Troyanskaya, Olga G, Mariani, Laura H., McClelland, Robyn L., Mooney, Sean D., Brown, Keith, Mariani, Laura H, Bomback, Andrew S, El-Achkar, Tarek M., Barasch, Jonathan M., Schaub, Jennifer A, Sharma, Kumar, Balis, Ulysses G. J., Barisoni, Laura, Waikar, Sushrut S., Lienczewski, Chrysta, Moledina, Dennis G, Alpers, Charles E, Jain, Sanjay, Knight, Richard, Balis, Ulysses G J, Steck, Becky, Dagher, Pierre C, O'Toole, John F, Blank, Kristina N, Laszik, Zoltan G., Alpers, Charles E., Azeloglu, Evren U., Himmelfarb, Jonathan, O'Toole, John F., McClelland, Robyn L, Iyengar, Ravi, Kellum, John A, Kellum, John A., Dighe, Ashveena L, de Boer, Ian H, Wilson, Francis Perry, Kidney Precision Medicine Project, Toto, Robert D, Hodgin, Jeffrey B., Moledina, Dennis G., Waikar, Sushrut S, Williams, Kayleen, Rosas, Sylvia E., Kiryluk, Krzysztof, Kretzler, Matthias, Palevsky, Paul M., Tuttle, Katherine R, Sedor, John R., Sedor, John R, Rosengart, Matthew R, Hacohen, Nir, Poggio, Emilio D, Schaub, Jennifer A., Eadon, Michael T., He, Yongqun, Barasch, Jonathan M, Menez, Steven, Mooney, Sean D, Dagher, Pierre C., Sarwal, Minnie M., Vazquez, Miguel A, Tuttle, Katherine R., Dighe, Ashveena L., Rosengart, Matthew R., Parikh, Chirag R, Sarwal, Minnie M, Blank, Kristina N., Zhang, Kun, Parikh, Chirag R., Bomback, Andrew S., Gaut, Joseph P, Laszik, Zoltan G, Rosas, Sylvia E, Poggio, Emilio D.   +86 more
core   +1 more source

Precision medicine and lymphoma [PDF]

Current Opinion in Hematology, 2018
Purpose of review The treatment of the germinal center lymphomas, diffuse large B cell (DLBCL) and follicular lymphoma, has changed little beyond the introduction of immunochemotherapies. However, there exists a substantial group of patients within both diseases for which improvements in care will involve appropriate tailoring ...
Heward, JA, Kumar, EA, Korfi, K, Okosun, J, Fitzgibbon, J   +4 more
openaire   +3 more sources

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Slotting metabolomics into routine precision medicine

, 2021
Introduction: Despite an impressive amount of metabolomics studies in animal models and humans, most findings have not yet translated into the clinical setting, and the road ahead remains still long.
Piras C., Atzori L., Noto A., Fanos V., Mussap M.   +4 more
core   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Precision Medicine [PDF]

Surgical Oncology Clinics of North America, 2020
Vijay P, Khatri, Nicholas J, Petrelli
openaire   +6 more sources

NEW CHALLENGES FOR THE NEONATAL INTENSIVE CARE UNIT: HOW TO IMPLEMENT MULTI-OMICS-DRIVEN PRECISION MEDICINE IN CLINICAL PRACTICE

, 2023
Precision medicine is the mainstream trend of contemporary medical development, and the neonatal intensive care unit (NICU) has become one of the important application scenarios of precision medicine.
XIAO Hui, YANG Lin, ZHOU Wenhao
core   +1 more source

Advancing Precision Medicine [PDF]

BioTechniques, 2019
Francesca Lake explores the latest goings on in techniques advancing precision medicine.
openaire   +3 more sources