Results 21 to 30 of about 1,197,472 (281)
Empowering precision medicine through high performance computing clusters [PDF]
, 2018 The role of High Performance Computing (HPC) in Medicine is greatly increase in these last years, moving from basic research to the clinics. With the advent of Next Generation Sequencing (NGS) technologies, diverse areas of human health have been ...
Castrignanò Tiziana +2 more
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Precision medicine informatics [PDF]
Journal of the American Medical Informatics Association, 2016 This special issue on precision medicine informatics flowed from the AMIA 2015 Translational Bioinformatics Summit theme of “Accelerating Precision Medicine”1 and President Obama’s 2015 State of the Union call “to give all of us access to the personalized information we need to keep ourselves and our families healthier.”2 The goal is to focus on the ...
Frey, Lewis J +2 more
openaire +3 more sources
A Path to Implement Precision Child Health Cardiovascular Medicine. [PDF]
, 2017 Congenital heart defects (CHDs) affect approximately 1% of live births and are a major source of childhood morbidity and mortality even in countries with advanced healthcare systems. Along with phenotypic heterogeneity, the underlying etiology of CHDs is
Brian Reemtsen +8 more
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Precision Medicine in Lung Cancer
European Medical Journal Oncology, 2020 Lung cancer has a devastating global impact, with diagnosis of more than 2 million new cases annually, and poor long-term survival. Recently, the landscape of lung cancer diagnosis, staging, and treatment has changed profoundly, with further developments
Esha Joshi
doaj +1 more source
Clinical proteomics for precision medicine: the bladder cancer case [PDF]
, 2017 Precision medicine can improve patient management by guiding therapeutic decision based on molecular characteristics. The concept has been extensively addressed through the application of –omics based approaches.
Frantzi, Maria +4 more
core +1 more source
Genomics and precision medicine for clinicians and scientists in hypertension [PDF]
, 2017 No abstract ...
Delles, Christian +2 more
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Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs [PDF]
, 2019 We endeavored to identify objective blood biomarkers for pain, a subjective sensation with a biological basis, using a stepwise discovery, prioritization, validation, and testing in independent cohorts design. We studied psychiatric patients, a high risk
Jones, T. +13 more
core +2 more sources
Review of precision cancer medicine: Evolution of the treatment paradigm. [PDF]
, 2020 In recent years, biotechnological breakthroughs have led to identification of complex and unique biologic features associated with carcinogenesis. Tumor and cell-free DNA profiling, immune markers, and proteomic and RNA analyses are used to identify ...
Fountzilas, Elena +3 more
core +1 more source
Engineering Precision Medicine [PDF]
Advanced Science, 2018 AbstractAdvances in genomic sequencing and bioinformatics have led to the prospect of precision medicine where therapeutics can be advised by the genetic background of individuals. For example, mapping cancer genomics has revealed numerous genes that affect the therapeutic outcome of a drug.
Wujin Sun +5 more
openaire +2 more sources
Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome. [PDF]
, 2017 In the 50 years since acute respiratory distress syndrome (ARDS) was first described, substantial progress has been made in identifying the risk factors for and the pathogenic contributors to the syndrome and in characterising the protein expression ...
Calfee, Carolyn S, Meyer, Nuala J
core +1 more source