Results 11 to 20 of about 470,101 (105)
Precision medicine informatics [PDF]
Journal of the American Medical Informatics Association, 2016 This special issue on precision medicine informatics flowed from the AMIA 2015 Translational Bioinformatics Summit theme of “Accelerating Precision Medicine”1 and President Obama’s 2015 State of the Union call “to give all of us access to the personalized information we need to keep ourselves and our families healthier.”2 The goal is to focus on the ...
Frey, Lewis J +2 more
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Precision Medicine for Obesity [PDF]
Digestive Disease Interventions, 2021 AbstractObesity is a multifactorial disease with a variable and underwhelming weight loss response to current treatment approaches. Precision medicine proposes a new paradigm to improve disease classification based on the premise of human heterogeneity, with the ultimate goal of maximizing treatment effectiveness, tolerability, and safety.
Lizeth Cifuentes +3 more
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Complementopathies and precision medicine [PDF]
Journal of Clinical Investigation, 2020 The renaissance of complement diagnostics and therapeutics has introduced precision medicine into a widened field of complement-mediated diseases. In particular, complement-mediated diseases (or complementopathies) with ongoing or published clinical trials of complement inhibitors include paroxysmal nocturnal hemoglobinuria, cold agglutinin disease ...
Eleni Gavriilaki, Robert A. Brodsky
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Engineering Precision Medicine [PDF]
Advanced Science, 2018 AbstractAdvances in genomic sequencing and bioinformatics have led to the prospect of precision medicine where therapeutics can be advised by the genetic background of individuals. For example, mapping cancer genomics has revealed numerous genes that affect the therapeutic outcome of a drug.
Wujin Sun +5 more
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Journal of Hematopathology, 2013 Contains fulltext : 125784.pdf (Publisher’s version ) (Closed access)
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Precision Medicine Requires Precision Laboratories [PDF]
The Journal of Molecular Diagnostics, 2017 This commentary highlights the validation study by Lih et al that supports the use of precision medicine for improved clinical trials.
Mangalathu S. Rajeevan +2 more
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Precision medicine at the crossroads [PDF]
Human Genomics, 2017 There are bioethical, institutional, economic, legal, and cultural obstacles to creating the robust-precompetitive-data resource that will be required to advance the vision of "precision medicine," the ability to use molecular data to target therapies to patients for whom they offer the most benefit at the least risk.
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Precision Medicine in Internal Medicine
Annals of Internal Medicine, 2019 Medicine has long sought to match diagnostic and treatment approaches to the particular needs and risks of individual patients. The decreasing cost and increasing ease of genetic sequencing have propelled the rise of precision medicine. Precision medicine aims to use genetic and other information to provide care tailored to the individual patient, with
Ronald J. Wapner +5 more
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Precision Medicine for Endocrinology [PDF]
International Journal of Endocrinology and Metabolism, 2016 In the recent decades, major biotechnological ad- vances have been achieved following the sudden escala- tion of disease-related molecular information, with the potential for greatly advancing patient care. The hu- man genome was depicted in year 2000, followed by the completion of the human genome project in 2003. Sci- entists have ignited a firestorm
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What Precisely Is Precision Medicine? [PDF]
Trends in Pharmacological Sciences, 2017 In some ways, precision has been a goal for medicine since its first inception. Swallow this herb for a headache, but rub that poultice on a sore foot. Different ailments, everyone realized, require tailored treatments to be effective. As understanding of biological complexity improved, especially with the breakthrough of genetic sequencing, we gained ...
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