Results 31 to 40 of about 1,104,938 (358)

Artificial intelligence and the future of diagnostic and therapeutic radiopharmaceutical development: in Silico smart molecular design [PDF]

open access: yes, 2021
Novel diagnostic and therapeutic radiopharmaceuticals are increasingly becoming a central part of personalized medicine. Continued innovation in the development of new radiopharmaceuticals is key to sustained growth and advancement of precision medicine.
arxiv   +1 more source

Precision Pharmacotherapy Enables Precision Medicine [PDF]

open access: yes, 2017
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138280/1/phar1998_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138280/2/phar1998 ...
Bishop, Jeffrey R., Ellingrod, Vicki L.
core   +1 more source

Precision medicine in bronchiectasis [PDF]

open access: yes, 2021
Bronchiectasis, due to its highly heterogenous nature, requires an individualised approach to therapy. Patients experience symptoms and exacerbations driven by a combination of impaired mucociliary clearance, airway inflammation and airway infection ...
Chalmers, James D., Pembridge, Thomas
core   +1 more source

Empowering precision medicine through high performance computing clusters [PDF]

open access: yes, 2018
The role of High Performance Computing (HPC) in Medicine is greatly increase in these last years, moving from basic research to the clinics. With the advent of Next Generation Sequencing (NGS) technologies, diverse areas of human health have been ...
Castrignanò Tiziana   +2 more
core   +2 more sources

Review of precision cancer medicine: Evolution of the treatment paradigm. [PDF]

open access: yes, 2020
In recent years, biotechnological breakthroughs have led to identification of complex and unique biologic features associated with carcinogenesis. Tumor and cell-free DNA profiling, immune markers, and proteomic and RNA analyses are used to identify ...
Fountzilas, Elena   +3 more
core   +1 more source

Precision Medicine in Lung Cancer

open access: yesEuropean Medical Journal Oncology, 2020
Lung cancer has a devastating global impact, with diagnosis of more than 2 million new cases annually, and poor long-term survival. Recently, the landscape of lung cancer diagnosis, staging, and treatment has changed profoundly, with further developments
Esha Joshi
doaj   +1 more source

Patient-centric trials for therapeutic development in precision oncology [PDF]

open access: yes, 2015
An enhanced understanding of the molecular pathology of disease gained from genomic studies is facilitating the development of treatments that target discrete molecular subclasses of tumours.
A Hollebecque   +60 more
core   +1 more source

Precision Medicine for Obesity [PDF]

open access: yesDigestive Disease Interventions, 2021
AbstractObesity is a multifactorial disease with a variable and underwhelming weight loss response to current treatment approaches. Precision medicine proposes a new paradigm to improve disease classification based on the premise of human heterogeneity, with the ultimate goal of maximizing treatment effectiveness, tolerability, and safety.
Lizeth Cifuentes   +3 more
openaire   +3 more sources

Precision-medicine-toolbox: An open-source python package for facilitation of quantitative medical imaging and radiomics analysis [PDF]

open access: yes, 2022
Medical image analysis plays a key role in precision medicine as it allows the clinicians to identify anatomical abnormalities and it is routinely used in clinical assessment. Data curation and pre-processing of medical images are critical steps in the quantitative medical image analysis that can have a significant impact on the resulting model ...
arxiv   +1 more source

Snapshot: Trial Types in Precision Medicine. [PDF]

open access: yes, 2020
Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but
Bergan, Raymond   +5 more
core  

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