Results 301 to 310 of about 1,044,728 (382)

Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology

Advanced Healthcare Materials, EarlyView.
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley   +1 more source

Recent Advances in Anti-Cancer Drugs. [PDF]

Int J Mol Sci
Neophytou CM.
europepmc   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

Correction: Preclinical evaluation of glycan-targeting monoclonal antibodies for bimodal near-infrared fluorescence and photoacoustic imaging of gastrointestinal cancers. [PDF]

EJNMMI Res
Houvast RD, Sier VQ, van Duijvenvoorde M, Baart VM, Schomann T, Chua J, Vankemmelbeke M, Durrant LG, Krijgsman D, de Heer P, Hassing GJ, Mieog JSD, Crobach ASLP, Burggraaf J, Kuppen PJK, Vahrmeijer AL, Sier CFM.   +16 more
europepmc   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source

Tailored antisense oligonucleotides for ultrarare CNS diseases: An experience-based best practice framework for individual patient evaluation. [PDF]

Mol Ther Nucleic Acids
Schüle R, Graessner H, Aartsma-Rus A, van Roon-Mom WMC, N=1 Collaborative (N1C), 1 Mutation 1 Medicine Consortium (1M1M), Synofzik M.   +6 more
europepmc   +1 more source

Synthesis and preclinical evaluation of novel L-cystine-based polyamide nanocapsules loaded with a fixed-dose combination of thymoquinone and doxorubicin for targeted pulmonary anticancer drug delivery

Hadeel Banat, Dalia Khalil Ali, Qais Jarrar, Esra’a Alomari, Eman Zmaily Dahmash   +4 more
openalex   +1 more source

Novel Animal Models for Multiple Sclerosis: R-Ras GTPases in Myelin Pathophysiology. [PDF]

Biomolecules
Esteban-Ortega GM, Garcia-Martin G, Cubelos B.   +2 more
europepmc   +1 more source

Antiviral Mechanisms and Preclinical Evaluation of Amantadine Analogs that Continue to Inhibit Influenza A Viruses with M2S31N-Based Drug Resistance

Ian Tietjen, Daniel Kwan, Annett Petrich, Roland Zell, Ivi Antoniadou, Agni F. M. Gavriilidou, Christina Tzitzoglaki, Michail Rallis, David Fedida, Francesc X. Sureda, Cato Mestdagh, Lieve Naesens, Salvatore Chiantia, F. Brent Johnson, Antonios Kolocouris   +14 more
openalex   +1 more source

Preclinical evaluation of DB-1419, a novel bifunctional and bispecific anti-B7-H3×PD-L1 antibody-drug conjugate

Chenggang Li, Jun Yao, Junjie Yang, Yu Zhang, Yang Qiu, Zhongyuan Zhu, Haiqing Hua   +6 more
openalex   +1 more source