Results 91 to 100 of about 6,422,598 (270)
Preclinical Imaging: an Essential Ally in Modern Biosciences [PDF]
Translational research is changing the practice of modern medicine and the way in which health problems are approached and solved. The use of small-animal models in basic and preclinical sciences is a major keystone for these kinds of research and development strategies, representing a bridge between discoveries at the molecular level and clinical ...
Sara Ferreira+11 more
openaire +5 more sources
Normal aging and Alzheimer's disease : hippocampal and episodic memory differences [PDF]
Alzheimer’s Disease (AD) and normal aging (NA) are characterized by structural brain changes as well as cognitive changes that appear over the lifespan.
Marnell, Ashley Michele
core +1 more source
With the ability to noninvasively image and monitor molecular processes within tumors, molecular imaging represents a fundamental tool for cancer scientists. In the current review, we describe emergent optical technologies for molecular imaging.
Giacomo Pirovano+3 more
semanticscholar +1 more source
Hyperoxic BOLD-MRI targeting tumor hypoxia may provide imaging biomarkers that represent breast cancer molecular subtypes without the use of injected contrast agents.
Silvester J. Bartsch+6 more
doaj +1 more source
Preclinical Stage Alzheimer's Disease Detection Using Magnetic Resonance Image Scans [PDF]
Alzheimer's disease is one of the diseases that mostly affects older people without being a part of aging. The most common symptoms include problems with communicating and abstract thinking, as well as disorientation. It is important to detect Alzheimer's disease in early stages so that cognitive functioning would be improved by medication and training.
arxiv
Accomplishments and challenges in stem cell imaging in vivo. [PDF]
Stem cell therapies have demonstrated promising preclinical results, but very few applications have reached the clinic owing to safety and efficacy concerns.
Bose, Rajendran JC, Mattrey, Robert F
core
Using the A/T/N framework to examine driving in preclinical Alzheimer’s disease [PDF]
The A/T/N classification system is the foundation of the 2018 NIA-AA Research Framework and is intended to guide the Alzheimer disease (AD) research agenda for the next 5–10 years.
Ances, Beau M+9 more
core +3 more sources
Spectral Imaging in Preclinical Research and Clinical Pathology [PDF]
Spectral imaging methods are attracting increased interest from researchers and practitioners in basic science, preclinical and clinical arenas. A combination of better labeling reagents and better optics creates opportunities to detect and measure multiple parameters at the molecular and cellular level.
Levenson, Richard+2 more
openaire +5 more sources
Background The poor prognosis of ovarian cancer patients is strongly related to peritoneal metastasis with the production of malignant ascites. However, it remains largely unclear how ascites in the peritoneal cavity influences tumor metabolism and ...
Qianlu Yang+11 more
doaj +1 more source
Small animal whole body imaging with metamaterial-inspired RF coil [PDF]
Preclinical magnetic resonance imaging often requires the entire body of an animal to be imaged with sufficient quality. This is usually performed by combining regions scanned with small coils with high sensitivity or long scans using large coils with low sensitivity. Here, a metamaterial-inspired design employing of a parallel array of wires operating
arxiv +1 more source