Results 81 to 90 of about 231,020 (192)

Micro-CT imaging of live insects using carbon dioxide gas-induced hypoxia as anesthetic with minimal impact on certain subsequent life history traits

BMC Zoology, 2017
Background Live imaging of whole invertebrates can be accomplished with X-ray micro-computed tomography (micro-CT) at 10-100 μm spatial resolution. However, image quality could be compromised by the movement of live subjects, producing image artefacts ...
Danny Poinapen, Joanna K. Konopka, Joseph U. Umoh, Chris J. D. Norley, Jeremy N. McNeil, David W. Holdsworth   +5 more
doaj   +1 more source

Noninvasive in vivo imaging of NF-κB activation predicts immunotherapy response in solid tumors

npj Imaging
Cancer immunotherapy improves survival, yet many patients exhibit primary or acquired resistance. We established a combinatorial immunotherapy (COMBO) consisting of tumor antigen-specific Th1 cells and dual immune checkpoint blockade and aimed to ...
Dimitri Stowbur, Roman Mehling, Philipp Knopf, Barbara Francisca Schörg, Dominik Sonanini, Danielle Arnold-Schild, Irene Gonzalez-Menendez, Leticia Quintanilla-Martinez, Birgit Fehrenbacher, Martin Schaller, Harald Carlsen, Snehlata Kumari, Bernd Jürgen Pichler, Manfred Kneilling   +13 more
doaj   +1 more source

Minimizing near-infrared autofluorescence in preclinical imaging with diet and wavelength selection. [PDF]

J Biomed Opt, 2023
Sun Y, Zhong X, Dennis AM.
europepmc   +1 more source

Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge. [PDF]

Mol Imaging Biol, 2023
Tavares AAS, Mezzanotte L, McDougald W, Bernsen MR, Vanhove C, Aswendt M, Ielacqua GD, Gremse F, Moran CM, Warnock G, Kuntner C, Huisman MC.   +11 more
europepmc   +1 more source

Disruption of normal brain distribution of [18F]Nifene to α4β2* nicotinic acetylcholinergic receptors in old B6129SF2/J mice and transgenic 3xTg-AD mice model of Alzheimer's disease: In Vivo PET/CT imaging studies

NeuroImage
The 3xTg-AD transgenic mouse model develops Aβ plaque and tau pathology and is purported to closely resemble pathological development in the human Alzheimer's disease (AD) brain.
Christopher Liang, Atsumi A. Okamoto, Fariha Karim, Shimako Kawauchi, Lusine Melkonyan, Tram B. Danh, Jogeshwar Mukherjee   +6 more
doaj   +1 more source

Comparison of postprocessing metrics in multimetabolic APT-weighted CEST and 2-deoxy-D-glucose-CEST-MRI for differentiating breast cancer subtypes in a murine model

European Radiology Experimental
Background Chemical exchange saturation transfer (CEST)-magnetic resonance imaging (MRI), particularly amide proton transfer-weighted (APTw)-CEST and 2-deoxy-D-glucose-CEST, holds promise for noninvasive molecular breast cancer (BC) characterization ...
Daniela Prinz, Silvester J. Bartsch, Joachim Friske, Martin Krššák, Daniela Laimer-Gruber, Thomas H. Helbich, Katja Pinker   +6 more
doaj   +1 more source

In vivo fluorescence imaging: success in preclinical imaging paves the way for clinical applications. [PDF]

J Nanobiotechnology, 2022
Refaat A, Yap ML, Pietersz G, Walsh APG, Zeller J, Del Rosal B, Wang X, Peter K.   +7 more
europepmc   +1 more source

Development of a WNT-selective oncolytic adenovirus for imaging the therapy of colorectal cancers.

, 2008
PhDIntroduction: The concept of oncolytic adenoviruses has been validated in preclinical studies but clinical trials have demonstrated that the virus spread remains limited and the virus fails to infect all cancer cells in a tumour.
Peerlinck, Inge D L, Peerlinck, Inge D. L.   +1 more
core  

Preclinical Imaging Evaluation of miRNAs' Delivery and Effects in Breast Cancer Mouse Models: A Systematic Review. [PDF]

Cancers (Basel), 2021
Orlandella FM, Auletta L, Greco A, Zannetti A, Salvatore G.   +4 more
europepmc   +1 more source

Data Curation for Preclinical and Clinical Multimodal Imaging Studies

, 2019
Purpose: In biomedical research, imaging modalities help discover pathological mechanisms to develop and evaluate novel diagnostic and theranostic approaches.
Yamoah, Grace Gyamfuah, Rosenhain, Stefanie, Wu, C., Vandeghinste, Bert, Leonardic, Kevin, Mannheim, Julia G. (author), Cao, Liji, Wu, Chao Wu, Gremse, Felix (author), Mannheim, Julia G., Wu, C. (author), Kiessling, Fabian, Beekman, Freek J., Yamoah, Grace Gyamfuah (author), Cao, Liji (author), Beekman, F.J., Rosenhain, Stefanie (author), Beekman, F.J. (author), Vandeghinste, Bert (author), Leonardic, Kevin (author), Gremse, Felix, Kiessling, Fabian (author)   +21 more
core   +1 more source