Micro-ultrasound for preclinical imaging [PDF]
Interface Focus, 2011 Over the past decade, non-invasive preclinical imaging has emerged as an important tool to facilitate biomedical discovery. Not only have the markets for these tools accelerated, but the numbers of peer-reviewed papers in which imaging end points and biomarkers have been used have grown dramatically.
F. Stuart Foster +2 more
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Clinical and Preclinical Imaging of Hepatosplenic Schistosomiasis. [PDF]
Trends in Parasitology, 2019 Schistosomiasis, a neglected tropical disease, is a major cause of chronic morbidity and disability, and premature death. The hepatosplenic form of schistosomiasis is characterized by hepatosplenomegaly, liver fibrosis, portal hypertension, and esophageal varices, whose rupture may cause bleeding and death.
Brice Masi +3 more
semanticscholar +4 more sources
Comparison of illumination geometry for lifetime-based measurements in whole-body preclinical imaging. [PDF]
J Biophotonics, 2018 Macroscopic fluorescence lifetime imaging (MFLI) has been proved to be an accurate tool to quantify Förster resonance energy transfer (FRET) lifetime‐based assessment of receptor‐ligand engagement in vitro and in vivo.
Sinsuebphon N +4 more
europepmc +2 more sources
Characterization of the Tumor Microenvironment and Tumor-Stroma Interaction by Non-invasive Preclinical Imaging. [PDF]
Front Oncol, 2017 Tumors are often characterized by hypoxia, vascular abnormalities, low extracellular pH, increased interstitial fluid pressure, altered choline-phospholipid metabolism, and aerobic glycolysis (Warburg effect).
Ramamonjisoa N, Ackerstaff E.
europepmc +2 more sources
Preclinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies. [PDF]
NPJ Regen Med, 2017 Regenerative medicine therapies hold enormous potential for a variety of currently incurable conditions with high unmet clinical need. Most progress in this field to date has been achieved with cell-based regenerative medicine therapies, with over a ...
Scarfe L +39 more
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Preclinical Ultrasound Imaging—A Review of Techniques and Imaging Applications [PDF]
Frontiers in Physics, 2020 Ultrasound imaging is a well-established clinical imaging technique providing real-time, quantitative anatomical and physiological information in humans.
C. Moran, A. Thomson
semanticscholar +5 more sources
Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging. [PDF]
Med Phys, 2015 In single photon emission computed tomography, the choice of the collimator has a major impact on the sensitivity and resolution of the system. Traditional parallel-hole and fan-beam collimators used in clinical practice, for example, have a relatively ...
Van Audenhaege K +5 more
europepmc +2 more sources
Positron Emission Tomography: Current Challenges and Opportunities for Technological Advances in Clinical and Preclinical Imaging Systems [PDF]
Annual Review of Biomedical Engineering, 2015 Positron emission tomography (PET) imaging is based on detecting two time-coincident high-energy photons from the emission of a positron-emitting radioisotope.
J.J. Vaquero, Paul E. Kinahan
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Preclinical Imaging Biomarkers for Postischaemic Neurovascular Remodelling. [PDF]
Contrast Media Mol Imaging, 2019 In the pursuit of understanding the pathological alterations that underlie ischaemic injuries, such as vascular remodelling and reorganisation, there is a need for recognising the capabilities and limitations of in vivo imaging techniques. Thus, this review presents contemporary published research of imaging modalities that have been implemented to ...
Gandhi R, Tsoumpas C.
europepmc +5 more sources
Apparent diffusion coefficient is highly reproducible on preclinical imaging systems: Evidence from a seven‐center multivendor study [PDF]
Journal of Magnetic Resonance Imaging, 2015 To evaluate between‐site agreement of apparent diffusion coefficient (ADC) measurements in preclinical magnetic resonance imaging (MRI) systems.
Sabrina Doblas +15 more
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