Results 91 to 100 of about 66,456,090 (253)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Author Correction: TAS0314, a novel multi-epitope long peptide vaccine, showed synergistic antitumor immunity with PD-1/PD-L1 blockade in HLA-A*2402 mice

Scientific Reports, 2022
Yuki Tanaka, Hiroshi Wada, Risa Goto, Toshihiro Osada, Keisuke Yamamura, Satoshi Fukaya, Atsushi Shimizu, Mitsuru Okubo, Kazuhisa Minamiguchi, Koichi Ikizawa, Eiji Sasaki, Teruhiro Utsugi   +11 more
doaj   +1 more source

Purkinje cells in eyeblink conditioning: a systematic review of methodological approaches in animal studies

Frontiers in Synaptic Neuroscience
BackgroundEyeblink conditioning is a canonical model of associative motor learning and has played a central role in theories of cerebellar plasticity.
Artem Gornov, Thiago C. Moulin, Thiago C. Moulin, Thiago C. Moulin, Anders Rasmussen, Fredrik Johansson   +5 more
doaj   +1 more source

Preclinical vaccines against mammary carcinoma. [PDF]

, 2013
Vaccines against human breast cancer are an unfulfilled promise. Despite decades of promising preclinical and clinical research, no vaccine is currently available for breast cancer patients.
Carla De Giovanni, DE GIOVANNI, CARLA, LOLLINI, PIER LUIGI, Federica Cavallo, NANNI, PATRIZIA, Cavallo F, Cavallo, Federica, Pier-Luigi Lollini, Patrizia Nanni   +8 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Biomedical applications of organoids in genetic diseases

Medical Review
Organoid technology has significantly transformed biomedical research by providing exceptional prospects for modeling human tissues and disorders in a laboratory setting.
Huang Wenhua, Jeong Seogsong, Kim Won, Chen Lei   +3 more
doaj   +1 more source

Comparative analyses of the hemostatic efficacy and surgical device performance of powdered oxidized regenerated cellulose and starch-based powder formulations

Research and Practice in Thrombosis and Haemostasis
Background: Hemostatic powders offer unique therapeutic advantages over other formulations, including ease of application and rapid distribution over large bleeding surfaces.
Marianne Stark, Allen Y. Wang, Brittny Corrigan, Henok G. Woldu, Samar Azizighannad, Gustavo Cipolla, Richard Kocharian, Hector De Leon   +7 more
doaj   +1 more source

A mixed-methods study to explore opinions of research translation held by researchers working in a Centre of Research Excellence in Australia [PDF]

, 2018
OBJECTIVE: There is a growing need for researchers to demonstrate impact, which is reliant on successful research translation. The Australian National Health and Medical Research Council funded a Centre of Research Excellence in Stroke Rehabilitation and
Nilsson, M, Cadilhac, D.A., Bernhardt, J, Lynch, E.A., Bernhardt, J., Ramanathan, SA, Nilsson, M., Lynch, EA, Ramanathan, S.A., Middleton, S, Middleton, S., Cadilhac, DA   +11 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source