Results 201 to 210 of about 790,668 (339)

Author Correction: Modulation of tumor immune microenvironment by TAS-115, a multi-receptor tyrosine kinase inhibitor, promotes antitumor immunity and contributes anti-PD-1 antibody therapy

Scientific Reports
Toshihiro Shibutani, Risa Goto, Isao Miyazaki, Akihiro Hashimoto, Takamasa Suzuki, Keiji Ishida, Tomonori Haruma, Toshihiro Osada, Takafumi Harada, Hidenori Fujita, Shuichi Ohkubo   +10 more
doaj   +1 more source

Protocol For Development Of A Tool To Help In The Reliability Assessment In Preclinical Research Studies (Raspress Tool)

, 2017
Kurinchi Selvan Gurusamy
openalex   +1 more source

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source

Rinaldo Bellomo: A clinician with a passion for preclinical research. [PDF]

Crit Care Resusc
May CN, Lankadeva YR, Bihari S.
europepmc   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Advancing preclinical research with reconstructed in vitro skin models mimicking non-healing wounds. [PDF]

Int J Pharm X
Daré RG, Lopes LB, Petri-Fink A, Rothen-Rutishauser B.   +3 more
europepmc   +1 more source

An Edible H2O2 Biosensor for Gastrointestinal Metabolites and Peroxidase Enzyme Quantification

Advanced Healthcare Materials, EarlyView.
We present an edible biosensor for gastric fluid analysis that integrates a caffeic acid–horseradish peroxidase redox system into an edible electrolyte‐gated transistor. The device enables rapid, low‐volume detection of H2O2 and, with minimal modification, metabolites and enzyme activity in simulated gastrointestinal conditions.
Valerio Francesco Annese, Elena Feltri, Pietro Rossi, Valerio Galli, Cristiano Bortolotti, João Paulo Vita Damasceno, Ivan K. Ilic, Dario Natali, Alessandro Luzio, Adrica Kyndiah, Mario Caironi   +10 more
wiley   +1 more source

Commissioning a clinical linac for preclinical research of heterogeneous intratumor irradiation with end-to-end tests. [PDF]

J Appl Clin Med Phys
Wang S, Li M, Li Z, Fan X, Yin Y, Dai T.
europepmc   +1 more source

A Concerted Appeal for International Cooperation in Preclinical Stroke Research [PDF]

, 2013
Ulrich Dirnagl, Antoine M. Hakim, Malcolm Macleod, Marc Fisher, David W. Howells, Stuart M. Alan, Gary K. Steinberg, Anna M. Planas, Johannes Boltze, Sean I. Savitz, Costantino Iadecola, Stephen Meairs   +11 more
openalex   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source