Results 221 to 230 of about 808,538 (334)

Moving beyond hydroxychloroquine: the novel lysosomal autophagy inhibitor ROC-325 shows significant potential in preclinical studies [PDF]

, 2019
Trace M. Jones, Claudia M. Espitia, Wei Wang, Steffan T. Nawrocki, Jennifer S. Carew   +4 more
openalex   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Large extracellular vesicles (microvesicles) in diabetic nephropathy: a systematic review of preclinical studies. [PDF]

Front Pharmacol
Ghanem SK, Abdelsalam SS, Bader L, Agouni A.   +3 more
europepmc   +1 more source

Preclinical Toxicity Studies-Tool of Drug Discovery

, 2017
Venkatesan, Ramanathan
openalex   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

The potential value of the use of berberine in depression: a systematic review and meta-analysis of preclinical studies. [PDF]

Front Pharmacol
Yao B, Long Z, Lin X, Chen G, Li X, Ye Z, Liu J.   +6 more
europepmc   +1 more source

Preclinical Hba1c Level Studies of Makardhwaj Ras and Maha Sankha Bati after Chronic Administration to Male Sprague-Dawley Rats

M. Nuruzzaman Neon, Sabiha K. Urmy, Anindya Barua, Md. Abu Adnan Khan, Manoth K. Biswas, Mohammad S.K. Choudhuri, Mohammad Mamun Sikder   +6 more
openalex   +2 more sources

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

Mitotherapy in Alzheimer's and Parkinson's diseases: A systematic review of preclinical studies. [PDF]

BMC Neurol
Modiri A, Hosseini L, Abolhasanpour N, Azizi H, Sadeh RN.   +4 more
europepmc   +1 more source

Impact of hyperglycemia on the efficacy of chemotherapy—A systematic review of preclinical studies

, 2017
Maaike C. Gerards, Daphne van der Velden, Joke W. Baars, Dees P. M. Brandjes, J. B. L. Hoekstra, Titia M. Vriesendorp, Victor E. A. Gerdes   +6 more
openalex   +1 more source