Results 41 to 50 of about 13,502,816 (309)

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Spatiotemporal characterization of a distinct nectin-3+ cell population in the developing and adult mouse retina

Scientific Reports
While Nectin-3 is a recognized marker for maintaining stem and progenitor “side populations” in non-neural epithelia, its role and distribution within the mammalian retina remain largely uncharacterized.
Agnieszka Lukomska, Patrycja Kieszek, Natalia Buczek, Mariusz Z. Ratajczak, Magdalena Kucia   +4 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

18F-FES radiation dosimetry preliminary estimates for preclinical studies based on voxelized phantom

Brazilian Journal of Radiation Sciences, 2022
Small animals, such as mice, are used in radiopharmaceutical biodistribution studies and innumerous others preclinical investigations involving ionizing radiation.
Andréa Vidal Ferreira, Ana Carolina Araujo Bispo, Christiane Silva Leite, Juliana Batista da Silva, Marcelo Mamede, Rodrigo Modesto Gadelha Gontijo, Bruno Melo Mendes   +6 more
doaj   +1 more source

Correction: AAV-Mediated Gene Therapy for Choroideremia: Preclinical Studies in Personalized Models. [PDF]

, 2015
Correction: AAV-Mediated Gene Therapy for Choroideremia: Preclinical Studies in Personalized ...
Paul Gadue (410480), Monika Kohnke, Bennicelli, Jeannette L., Etiena Basner-Tschakarjan (410473), Helen Mac, Aaron D. Black (410475), Zhou, Shangzhen, Albert M. Maguire (277813), Deborah L. French (410482), Rajashekhar Gaddameedi (410472), Black, Aaron D., Maguire, Albert M., Etiena Basner-Tschakarjan, Helen Mac (410478), Jean Bennett (277818), Albert M Maguire, Bennett, Jean, Deborah L French, Jason A Mills, Aaron D Black, Paul Gadue, Alexandrov, Krill, Jean Bennett, Basner-Tschakarjan, Etiena, Chung, Daniel C., Mills, Jason A., Daniel C Chung, Sullivan, Lisa, Jason A. Mills (410471), Monika Kohnke (410474), Shangzhen Zhou, Krill Alexandrov (410476), Jeannette L Bennicelli, Vidyullatha Vasireddy (348902), Gadue, Paul, Vasireddy, Vidyullatha, Rajashekhar Gaddameedi, Lisa Sullivan (410479), Shangzhen Zhou (410477), Daniel C. Chung (247807), Jeannette L. Bennicelli (410481), Vidyullatha Vasireddy, Gaddameedi, Rajashekhar, French, Deborah L., Kohnke, Monika, Mac, Helen, Lisa Sullivan, Krill Alexandrov   +47 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Pyronaridine tetraphosphate is an efficacious antiviral and anti-inflammatory active against multiple highly pathogenic coronaviruses

mBio, 2023
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), continues to be one of the largest dangers to human health around the world.
Jeremy Ardanuy, Robert Johnson, Carly Dillen, Louis Taylor, Holly Hammond, Stuart Weston, Matthew Frieman   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Immunohistochemical studies of the enteric nervous system and interstitial cells of Cajal in the canine stomach

Onderstepoort Journal of Veterinary Research, 2013
The distribution of interstitial cells of Cajal (ICC), the probable pacemakers in gastrointestinal motility, was investigated using an antigenic marker of gastric ICC known as C-Kit.
Colin Musara, Camille Vaillant
doaj  

Commensal Microbiota Effects on Craniofacial Skeletal Growth and Morphology

JBMR Plus, 2023
Microbes colonize anatomical sites in health to form commensal microbial communities (e.g., commensal gut microbiota, commensal skin microbiota, commensal oral microbiota).
Joy E. Gerasco, Jessica D. Hathaway‐Schrader, Nicole A. Poulides, Matthew D. Carson, Naoto Okhura, Caroline Westwater, Nan E. Hatch, Chad M. Novince   +7 more
doaj   +1 more source