Results 181 to 190 of about 781,590 (289)

Extracellular fluid viscosity influences the mechanics and migration of MDA‐MB‐231 cells in a macromolecule‐dependent manner

open access: yesThe FEBS Journal, EarlyView.
Macromolecule‐dependent increases in extracellular fluid viscosity alter cell phenotype. These distinct macromolecules create different extracellular environments that modulate cell morphology and mechanoprotein expression, migration and invasion capacity, and cellular mechanical properties.
Ian M. Smith   +6 more
wiley   +1 more source

Methionine Regulates Antitumour Function of CD8+ T Cells Through Polyamine Synthesis

open access: yesImmunology, EarlyView.
Methionine restriction in vitro enhances CD8+ T cell effector function by suppressing polyamine synthesis and progressively induces the co‐expression of PD‐1 and TIM‐3. Consistently, sustained dietary methionine restriction diminishes the efficacy of adoptive T cell therapy (ACT) and promotes the expression of terminal exhaustion‐associated markers ...
Tian Zhao   +16 more
wiley   +1 more source

A Horse Race of Machine‐Learning Methods to Predict Banking Crises

open access: yesInternational Finance, EarlyView.
ABSTRACT To examine if one machine‐learning model can consistently elucidate financial vulnerabilities, both over time and across levels of development, this paper applies 13 machine‐learning algorithms to evaluate comparative forecasting performance across several banking crises.
Emile du Plessis
wiley   +1 more source

Layer‐by‐layer soft‐tissue effects on flexion–extension‐dominant passive ex vivo limb joint ROM in quadrupedal mammals: An anatomical contribution to a morphofunctional framework

open access: yesJournal of Anatomy, EarlyView.
Layer‐by‐layer passive ex vivo assessment of flexion–extension‐dominant limb joint ROM across rabbit, pudu deer, chilla fox and pig revealed joint‐, tissue‐ and taxon‐specific responses to progressive tissue removal. Proximal joints often showed increasing ROM, whereas distal joints often showed non‐monotonic responses.
Paul Medina‐González   +4 more
wiley   +1 more source

Eccentric Occlusal Loads Remodel the Dentoalveolar and Temporomandibular Biomechanical Unit in Rats

open access: yesJournal of Oral Rehabilitation, EarlyView.
Eccentric occlusal loads remodel the dentoalveolar and temporomandibular joints in the masticatory biomechanical unit in rats. (A) Bite block as an occlusal rise (OR) on the rat maxillary first molar (green region) is shown. (B) 18F‐NaF Positron emission tomography localised regions of higher metabolic activity (higher uptake in the left condyle ...
Haochen Ci   +14 more
wiley   +1 more source

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